Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9986523 | 0.81 | LMNA (0.47) | HTTALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL4855123 | 0.76 | GAA (0.46) | GAACXCR2 | |
| SCHEMBL3454613 | 0.75 | KDM4E (0.46) | SMN1; SMN2RAB9AGAAHTTALDH1A1 | |
| SCHEMBL25314257 | 0.74 | SMN1; SMN2 (0.68) | SMN1; SMN2RAB9AGAAHTTL3MBTL1 | |
| SCHEMBL1129590 | 0.74 | CTSD (0.45) | GAAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6538745 | 0.74 | SLC6A3 (0.46) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL29691116 | 0.74 | LIPG (0.41) | SMN1; SMN2ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL18865621 | 0.74 | LIPG (0.41) | SMN1; SMN2ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL2568848 | 0.73 | SMN1; SMN2 (0.66) | SMN1; SMN2RAB9AGAAHTTL3MBTL1 | |
| SCHEMBL21929414 | 0.73 | KMT2A (0.68) | SMN1; SMN2RAB9AGAAHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11168080-B2 | Dynamin-1-like protein inhibitors | MITOBRIDGE, INC. (US) | 2021-11-09 | — | — | US | disclosed |
| US-11168080-B2 | Dynamin-1-like protein inhibitors | MITOBRIDGE, INC. (US) | 2021-11-09 | — | — | US | disclosed |
| US-20200131172-A1 | DYNAMIN-1-LIKE PROTEIN INHIBITORS | Astellas Engineered Small Molecules US, Incorporated | 2020-04-30 | — | — | US | disclosed |
| US-20200131172-A1 | DYNAMIN-1-LIKE PROTEIN INHIBITORS | Astellas Engineered Small Molecules US, Incorporated | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11168080-B2 | Dynamin-1-like protein inhibitors | DNM1L, DNM1, DNM2 | SMN1; SMN2 2970/4885RAB9A 268/4885GAA 1161/4885 |
| US-20200131172-A1 | DYNAMIN-1-LIKE PROTEIN INHIBITORS | DNM1L, DNM1, DNM2 | SMN1; SMN2 2970/4885RAB9A 268/4885GAA 1161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.