SCHEMBL21887692

SCHEMBL21887692

O=C1C=CC(=C2C=CC(=O)C(Oc3ccccc3)=C2)C=C1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CES2 O00748 7/20 0.45
CES1 P23141 7/20 0.45
GAPDH P04406 2/20 0.45
MAOA P21397 3/20 0.44
MAOB P27338 3/20 0.44
ERBB2 P04626 1/20 0.37
HSD17B3 P37058 1/20 0.37
LTA4H P09960 1/20 0.37
TSHR P16473 1/20 0.37
MGLL Q99685 1/20 0.35
ALOX5 P09917 1/20 0.34
GSTP1 P09211 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3363900 0.87 MAOA (0.55) CES2CES1GAPDHMAOAMAOB
SCHEMBL13879154 0.75 CES2 (0.64) CES2CES1GAPDHMAOALTA4H
SCHEMBL9077007 0.69 ERBB2 (0.41) CES2CES1GAPDHMAOAMAOB
SCHEMBL6432470 0.68 LTA4H (0.55) CES2CES1GAPDHMAOAMAOB
Diphenylether SCHEMBL6002153 0.66 LTA4H (0.60) MAOAMAOBLTA4HTSHRMGLL
Diphenylether SCHEMBL29209296 0.65 MAOA (0.67) CES2CES1GAPDHMAOAMAOB
SCHEMBL9077009 0.64 MAOA (0.46) CES2CES1MAOAMAOBERBB2
SCHEMBL21887167 0.62 ERBB2 (0.70) ERBB2ALOX5
SCHEMBL4468407 0.62 GAPDH (1.00) CES2CES1GAPDHMAOAMAOB
SCHEMBL2751602 0.62 ALDH1A1 (0.73) MAOAMAOBERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11215935-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-01-04 US disclosed
US-11169455-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJIFILM BUSINESS INNOVATION CORP. (JP) 2021-11-09 US disclosed
US-20200341393-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2020-10-29 US disclosed
US-20200341392-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2020-10-29 US disclosed
US-10754266-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2020-08-25 US disclosed
US-20200096884-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO.,LTD. (JP) 2020-03-26 US disclosed