Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | ALDH5A1 | P51649 | 3/20 | 0.52 |
| ▸ | ABAT | P80404 | 3/20 | 0.52 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.52 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29465560 | 1.00 | KDM4E (0.64) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL4367977 | 0.82 | KDM4E (0.48) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL1922774 | 0.82 | KDM4E (0.64) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL29887017 | 0.79 | KDM4E (0.50) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL6619511 | 0.79 | HSD17B1 (0.59) | KDM4EPTGS2RAB9ATRIM24TRIM33 | |
| SCHEMBL29389102 | 0.78 | ALDH1A1 (0.52) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL48607 | 0.78 | ALDH1A1 (0.52) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| Protocatechualdehyde SCHEMBL36350 | 0.78 | KDM4E (1.00) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| Protocatechualdehyde SCHEMBL9512877 | 0.78 | KDM4E (1.00) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| Protocatechualdehyde SCHEMBL29349539 | 0.78 | KDM4E (1.00) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 936 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120081885-A | Substituted phenyl glycoside compound and preparation method and application thereof | 浙江大学 | 2025-06-03 | — | — | CN | claimed |
| CN-119439624-A | Imine-based high-performance ultraviolet shielding photoresist and preparation method thereof | 中国工程物理研究院激光聚变研究中心 | 2025-02-14 | — | — | CN | claimed |
| CN-117658887-A | Fluorescent probe for detecting heavy water content in water | 遵义医科大学 | 2024-03-08 | — | — | CN | claimed |
| CN-117623931-A | Preparation method of safe and environment-friendly mono-nitro aromatic hydrocarbon | 清源创新实验室 | 2024-03-01 | — | — | CN | claimed |
| CN-115650930-B | Diaryl ethylene fluorescent molecular material, diaryl ethylene hydrogel material, and preparation and application thereof | 浙江大学杭州国际科创中心 | 2023-11-03 | — | — | CN | claimed |
| CN-115650930-A | Diarylethene fluorescent molecular material, diarylethene hydrogel material, preparation and application thereof | 浙江大学杭州国际科创中心 | 2023-01-31 | — | — | CN | claimed |
| CN-114634501-A | 3, 5-diaryl-thiazolidone-azo chain-indolone derivative and preparation method and application thereof | 复旦大学 | 2022-06-17 | — | — | CN | claimed |
| CN-103304408-A | Preparation method of roflumilast intermediate 3-cyclopropyl methoxy-4-difluoromethoxybenzoic acid | WEIHAI DISU PHARMACEUTICAL CO LTD | 2013-09-18 | — | — | CN | claimed |
| EP-1778011-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF UBIQUITIN CONJUGATING DISORDERS | Hygeia Biological Systems (US) | 2007-05-02 | — | — | EP | claimed |
| WO-2006020681-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF UBIQUITIN CONJUGATING DISORDERS | HYGEIA BIOLOGICAL SYSTEMS (US) | 2006-02-23 | — | — | WO | claimed |
| US-20060035890-A1 | Compounds and methods for the treatment of ubiquitin conjugating disorders | AMIT BANERJEE | 2006-02-16 | — | — | US | claimed |
| US-20040014796-A1 | Novel compounds and compositions as cathepsin S inhititors | AXYS PHARMACEUTICALS, INC. | 2004-01-22 | — | — | US | claimed |
| US-6492362-B1 | Compounds and compositions as cathepsin S inhibitors | AXYS PHARMACEUTICALS, INC. | 2002-12-10 | — | — | US | claimed |
| WO-2001019808-A1 | CHEMICAL COMPOUNDS AND COMPOSITIONS AND THEIR USE AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | claimed |
| US-12630509-B2 | Heterocyclic NMDA antagonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2026-05-19 | — | — | US | disclosed |
| CN-122050597-A | End-to-end drug design method and device based on multi-agent cooperation | 深圳大学 | 2026-05-15 | — | — | CN | disclosed |
| EP-4055016-B1 | GPR52 MODULATOR COMPOUNDS | NXERA PHARMA UK LTD (GB) | 2026-04-29 | — | — | EP | disclosed |
| EP-0197677-A2 | Halogen-containing, optically active liquid crystal compound and liquid crystal composition containing same | Chisso Corporation (JP) | 1986-10-15 | — | — | EP | disclosed |
| US-3972945-A | Process for the selective synthesis of salicylaldehydes | THE GARRETT CORPORATION (US) | 1976-08-03 | — | — | US | disclosed |
| US-3972945-A | Process for the selective synthesis of salicylaldehydes | THE GARRETT CORPORATION (US) | 1976-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630509-B2 | Heterocyclic NMDA antagonists | GRIN1, GRIN3A, GRIN2B | KDM4E 575/4885PTGS2 1981/4885RAB9A 1701/4885 |
| US-20040014796-A1 | Novel compounds and compositions as cathepsin S inhititors | CTSS, CTSB, CTSE | KDM4E 4465/4885PTGS2 1829/4885RAB9A 401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.