SCHEMBL21959862

SCHEMBL21959862

CC(C)N1CC(=O)N([C@@H](C)C(=O)OCc2ccccc2)CC1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSL P07711 4/20 0.48
CTSB P07858 1/20 0.48
ALDH1A1 P00352 5/20 0.45
MAPK1 P28482 2/20 0.42
NPC1 O15118 1/20 0.42
GAA P10253 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HPGD P15428 2/20 0.42
MAPT P10636 1/20 0.41
HSD17B10 Q99714 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A3 Q01959 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
ELANE P08246 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21959850 0.90 L3MBTL1 (0.47) CTSLCTSBALDH1A1MAPK1NPC1
SCHEMBL21960350 0.86 CTSB (0.47) CTSLCTSBALDH1A1MAPK1NPC1
SCHEMBL21960352 0.86 CTSB (0.47) CTSLCTSBALDH1A1MAPK1NPC1
SCHEMBL21878243 0.82 CTSL (0.48) CTSLCTSBALDH1A1MAPK1NPC1
SCHEMBL15126843 0.77 L3MBTL1 (0.46) CTSLCTSBALDH1A1NPC1RAB9A
SCHEMBL16132827 0.77 MEN1 (0.51) CTSLCTSBALDH1A1NPC1RAB9A
SCHEMBL11063207 0.77 ALDH1A1 (0.50) CTSLCTSBALDH1A1MAPK1NPC1
SCHEMBL15110433 0.76 MEN1 (0.50) CTSLALDH1A1GAAMAPTKMT2A
SCHEMBL15110164 0.76 MEN1 (0.51) ALDH1A1MAPK1MAPTL3MBTL1KMT2A
SCHEMBL908124 0.76 KDM4E (0.49) ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11084794-B2 Controlled cyclization of peptoids to form chiral diketopiperazines TRIAD NATIONAL SECURITY, LLC (US) 2021-08-10 US disclosed
US-20200131140-A1 CONTROLLED CYCLIZATION OF PEPTOIDS TO FORM CHIRAL DIKETOPIPERAZINES TRIAD NATIONAL SECURITY, LLC (US) 2020-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11084794-B2 Controlled cyclization of peptoids to form chiral diketopiperazines NPPA, NPEPPS, RRP15 CTSL 638/4885CTSB 2277/4885ALDH1A1 4849/4885
US-20200131140-A1 CONTROLLED CYCLIZATION OF PEPTOIDS TO FORM CHIRAL DIKETOPIPERAZINES NPPA, NPEPPS, RRP15 CTSL 638/4885CTSB 2277/4885ALDH1A1 4849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.