Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | IL1RN | P18510 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21960350 | 1.00 | CTSB (0.47) | CTSBCTSLALDH1A1IL1RNERAP2 | |
| SCHEMBL21959862 | 0.86 | CTSL (0.48) | CTSBCTSLALDH1A1MAPK1NPC1 | |
| SCHEMBL21959528 | 0.84 | GPBAR1 (0.41) | CTSBCTSLALDH1A1IL1RNERAP2 | |
| SCHEMBL7407155 | 0.83 | APOBEC3A (0.46) | CTSBALDH1A1IL1RNERAP2ERAP1 | |
| SCHEMBL1289870 | 0.80 | SLC1A2 (0.50) | CTSBALDH1A1IL1RNERAP2ERAP1 | |
| SCHEMBL19388177 | 0.80 | ATM (0.44) | CTSBCTSLALDH1A1IL1RNERAP2 | |
| SCHEMBL21878243 | 0.80 | CTSL (0.48) | CTSBCTSLALDH1A1MAPK1NPC1 | |
| SCHEMBL27058220 | 0.78 | ALDH1A1 (0.42) | CTSBCTSLALDH1A1IL1RNERAP2 | |
| SCHEMBL3736402 | 0.77 | ALDH1A1 (0.47) | CTSBCTSLALDH1A1IL1RNERAP2 | |
| SCHEMBL21959850 | 0.77 | L3MBTL1 (0.47) | CTSBCTSLALDH1A1MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11084794-B2 | Controlled cyclization of peptoids to form chiral diketopiperazines | TRIAD NATIONAL SECURITY, LLC (US) | 2021-08-10 | — | — | US | disclosed |
| US-20200131140-A1 | CONTROLLED CYCLIZATION OF PEPTOIDS TO FORM CHIRAL DIKETOPIPERAZINES | TRIAD NATIONAL SECURITY, LLC (US) | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11084794-B2 | Controlled cyclization of peptoids to form chiral diketopiperazines | NPPA, NPEPPS, RRP15 | CTSB 2277/4885CTSL 638/4885ALDH1A1 4849/4885 |
| US-20200131140-A1 | CONTROLLED CYCLIZATION OF PEPTOIDS TO FORM CHIRAL DIKETOPIPERAZINES | NPPA, NPEPPS, RRP15 | CTSB 2277/4885CTSL 638/4885ALDH1A1 4849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.