SCHEMBL21971590

SCHEMBL21971590

CC(C)(C)c1cccc2oc3cccc(-c4ccccc4)c3c12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 1/20 0.35
▸ ALDH1A1 P00352 6/20 0.34
▸ TSHR P16473 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ RAB9A P51151 2/20 0.34
▸ LIMK1 P53667 2/20 0.34
▸ CLK4 Q9HAZ1 2/20 0.34
▸ KDM4E B2RXH2 2/20 0.34
▸ PLK4 O00444 1/20 0.34
▸ MAPK9 P45984 1/20 0.34
▸ AKT3 Q9Y243 1/20 0.34
▸ MAOB P27338 1/20 0.34
▸ CDC14B O60729 2/20 0.34
▸ CDC14A Q9UNH5 2/20 0.34
▸ PTPN5 P54829 1/20 0.34
▸ KMT2A Q03164 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ PDCD1 Q15116 1/20 0.33
▸ CD274 Q9NZQ7 1/20 0.33
▸ HSD17B10 Q99714 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25456439 0.84 CHEK1 (0.50) ALDH1A1TSHRTDP1RAB9ALIMK1
SCHEMBL21972231 0.84 CDC14B (0.34) ALDH1A1RAB9ALIMK1CLK4KDM4E
SCHEMBL26254244 0.84 PDCD1 (0.36) ALDH1A1TSHRRAB9ALIMK1CLK4
SCHEMBL12203195 0.83 ALDH1A1 (0.44) ALDH1A1RAB9ALIMK1CLK4KDM4E
SCHEMBL26190221 0.83 CA2 (0.48) CA2ALDH1A1TSHRTDP1KDM4E
SCHEMBL21972046 0.82 RXRA (0.36) CA2ALDH1A1RAB9ALIMK1CLK4
SCHEMBL16282383 0.81 CDC14B (0.42) ALDH1A1CDC14BCDC14AKMT2AMEN1
SCHEMBL22199376 0.80 ALDH1A1 (0.36) ALDH1A1TSHRRAB9ALIMK1CLK4
SCHEMBL21972236 0.80 RAB9A (0.34) ALDH1A1TSHRRAB9ALIMK1CLK4
SCHEMBL25494166 0.77 CA2 (0.33) CA2GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 — — US disclosed
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 — — US disclosed
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 — — US disclosed
US-11864458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-01-02 — — US disclosed
US-11832510-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-28 — — US disclosed
US-20230371360-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 — — US disclosed
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 — — US disclosed
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 — — US disclosed
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 — — US disclosed
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 — — US disclosed
US-20230041530-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-02-09 — — US disclosed
US-20230002430-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-01-05 — — US disclosed
US-20230002417-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-01-05 — — US disclosed
US-20220402953-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSITY DISPLAY CORPORATION (US) 2022-12-22 — — US disclosed
US-20220396596-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-12-15 — — US disclosed
US-20220393117-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-12-08 — — US disclosed
US-20210305520-A1 ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-09-30 — — US disclosed
US-20210066622-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-03-04 — — US disclosed
US-20200220090-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-07-09 — — US disclosed
US-20200140471-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-05-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (17 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220393117-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NPY1R, NPY2R, KISS1R CA2 3575/4885ALDH1A1 1485/4885TSHR 163/4885
US-11832510-B2 Organic electroluminescent materials and devices OSBP, OCIAD2, OCIAD1 CA2 4445/4885ALDH1A1 526/4885TSHR 4292/4885
US-12035618-B2 Electroluminescent devices ELAVL1, ELAVL3, JUND CA2 4698/4885ALDH1A1 1948/4885TSHR 4120/4885
US-20210066622-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, JUND CA2 3031/4885ALDH1A1 3477/4885TSHR 3620/4885
US-20220396596-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, DRD3 CA2 3380/4885ALDH1A1 1664/4885TSHR 2845/4885
US-20230371360-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CHRM1, L1CAM, SOD1 CA2 3651/4885ALDH1A1 831/4885TSHR 1035/4885
US-20200140471-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 CA2 4546/4885ALDH1A1 268/4885TSHR 3604/4885
US-11864458-B2 Organic electroluminescent materials and devices RAP1A, L1CAM, SOD1 CA2 2642/4885ALDH1A1 165/4885TSHR 939/4885
US-20210305520-A1 ELECTROLUMINESCENT DEVICES ELAVL1, ELAVL3, JUND CA2 4698/4885ALDH1A1 1948/4885TSHR 4120/4885
US-20230002417-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 CA2 4165/4885ALDH1A1 81/4885TSHR 4211/4885
US-20200220090-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 CA2 4170/4885ALDH1A1 612/4885TSHR 4571/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG CA2 4584/4885ALDH1A1 149/4885TSHR 2736/4885
US-20230002430-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CHRM1, L1CAM, SOD1 CA2 3653/4885ALDH1A1 812/4885TSHR 1025/4885
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, ROS1 CA2 3295/4885ALDH1A1 569/4885TSHR 189/4885
US-20220402953-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP CA2 4231/4885ALDH1A1 134/4885TSHR 3725/4885
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, OXSR1 CA2 3314/4885ALDH1A1 728/4885TSHR 159/4885
US-20230041530-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CHRM1 CA2 2986/4885ALDH1A1 1845/4885TSHR 355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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