SCHEMBL21972046

SCHEMBL21972046

CC(C)(C)c1cc(-c2cccc3oc4cccc(C(C)(C)C)c4c23)cc(C(C)(C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RXRA P19793 2/20 0.36
▸ RXRB P28702 2/20 0.36
▸ PTPN5 P54829 1/20 0.35
▸ KIF11 P52732 1/20 0.33
▸ CA2 P00918 1/20 0.32
▸ RXRG P48443 1/20 0.32
▸ S1PR1 P21453 2/20 0.31
▸ S1PR3 Q99500 1/20 0.31
▸ ALDH1A1 P00352 2/20 0.30
▸ MAPT P10636 2/20 0.30
▸ NPC1 O15118 1/20 0.30
▸ PLA2G1B P04054 1/20 0.30
▸ NFKB1 P19838 1/20 0.30
▸ CASP3 P42574 1/20 0.30
▸ RAB9A P51151 1/20 0.30
▸ NFKB2 Q00653 1/20 0.30
▸ RELA Q04206 1/20 0.30
▸ SENP8 Q96LD8 1/20 0.30
▸ SENP7 Q9BQF6 1/20 0.30
▸ SENP6 Q9GZR1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22199331 0.85 ALDH1A1 (0.33) RXRARXRBALDH1A1MAPTCHEK1
SCHEMBL25768507 0.85 RXRA (0.33) RXRARXRBALDH1A1MAPT
SCHEMBL22199391 0.84 RXRB (0.36) RXRARXRBKIF11RXRGS1PR1
SCHEMBL21971590 0.82 CA2 (0.35) PTPN5CA2ALDH1A1MAPTRAB9A
SCHEMBL24433630 0.82 RXRA (0.34) RXRARXRBKIF11RXRGALDH1A1
SCHEMBL25456439 0.80 CHEK1 (0.50) ALDH1A1MAPTNPC1RAB9AKDM4E
SCHEMBL26190221 0.79 CA2 (0.48) KIF11CA2ALDH1A1MAPTKDM4E
SCHEMBL24433579 0.79 RXRA (0.38) RXRARXRBRXRGALDH1A1MAPT
SCHEMBL26199010 0.79 ALDH1A1 (0.33) RXRARXRBALDH1A1MAPTNPC1
SCHEMBL25523477 0.79 RXRA (0.38) RXRARXRBRXRGALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 — — US disclosed
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 — — US disclosed
US-11864458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-01-02 — — US disclosed
US-20230371360-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 — — US disclosed
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 — — US disclosed
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 — — US disclosed
US-20230357296-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 — — US disclosed
US-11802136-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-31 — — US disclosed
US-11802136-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-31 — — US disclosed
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 — — US disclosed
US-20230159578-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-25 — — US disclosed
US-20230157154-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-18 — — US disclosed
US-20230147066-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 — — US disclosed
US-20230145950-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-11 — — US disclosed
US-20230140064-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-04 — — US disclosed
US-20230049161-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-02-16 — — US disclosed
US-20220402953-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSITY DISPLAY CORPORATION (US) 2022-12-22 — — US disclosed
US-20220153769-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-19 — — US disclosed
US-20220069241-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-03-03 — — US disclosed
US-20200140471-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-05-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (18 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157154-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, GLRA3 RXRA 905/4885RXRB 941/4885PTPN5 4392/4885
US-20230345812-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OPRD1, OCIAD2 RXRA 361/4885RXRB 412/4885PTPN5 3558/4885
US-20230371360-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CHRM1, L1CAM, SOD1 RXRA 621/4885RXRB 562/4885PTPN5 4025/4885
US-20230357296-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, OXER1, LBR RXRA 138/4885RXRB 160/4885PTPN5 2394/4885
US-20200140471-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OCIAD1, OCIAD2 RXRA 1861/4885RXRB 1833/4885PTPN5 4861/4885
US-11864458-B2 Organic electroluminescent materials and devices RAP1A, L1CAM, SOD1 RXRA 248/4885RXRB 262/4885PTPN5 4076/4885
US-20230147066-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, SSB, MCOLN3 RXRA 1443/4885RXRB 930/4885PTPN5 4488/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG RXRA 1472/4885RXRB 1490/4885PTPN5 4785/4885
US-20220069241-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CHRM1, LBR, CNKSR1 RXRA 443/4885RXRB 263/4885PTPN5 3912/4885
US-20230159578-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, DRD3 RXRA 469/4885RXRB 384/4885PTPN5 4704/4885
US-20230140064-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CCND3 RXRA 420/4885RXRB 295/4885PTPN5 4593/4885
US-20230145950-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NR1D2, NR1H2, NR1D1 RXRA 590/4885RXRB 333/4885PTPN5 4415/4885
US-20230049161-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, AOC2, OCIAD1 RXRA 1141/4885RXRB 740/4885PTPN5 3323/4885
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, ROS1 RXRA 894/4885RXRB 958/4885PTPN5 4415/4885
US-20220402953-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP RXRA 2923/4885RXRB 2880/4885PTPN5 4710/4885
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, OXSR1 RXRA 262/4885RXRB 336/4885PTPN5 3746/4885
US-20220153769-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ODC1, OCIAD1, OCIAD2 RXRA 4188/4885RXRB 3972/4885PTPN5 4860/4885
US-11802136-B2 Organic electroluminescent materials and devices OSBP, OCIAD1, OCIAD2 RXRA 1861/4885RXRB 1833/4885PTPN5 4861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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