SCHEMBL2200187

SCHEMBL2200187

CC(C)c1cccc(C(C)C)c1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.55
LMNA P02545 4/20 0.55
CYP1A2 P05177 2/20 0.55
CYP3A4 P08684 2/20 0.55
GABRG2 P18507 2/20 0.55
GABRB3 P28472 2/20 0.55
GABRB2 P47870 2/20 0.55
GABRB1 P18505 2/20 0.55
FAAH O00519 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
HPGD P15428 1/20 0.55
TSHR P16473 1/20 0.55
PTGS1 P23219 1/20 0.55
SLC6A2 P23975 1/20 0.55
HTR2C P28335 1/20 0.55
GABRA5 P31644 1/20 0.55
GABRA3 P34903 1/20 0.55
HTR2B P41595 1/20 0.55
GABRA2 P47869 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16951136 0.88 GABRA1 (0.44) GABRA1LMNACYP1A2CYP3A4GABRG2
SCHEMBL423182 0.87 CYP1A2 (0.68) GABRA1LMNACYP1A2CYP3A4GABRG2
SCHEMBL9321395 0.86 GABRA1 (0.43) GABRA1LMNACYP1A2CYP3A4GABRG2
SCHEMBL2737288 0.85 LMNA (0.46) GABRA1LMNACYP1A2CYP3A4GABRG2
SCHEMBL22989563 0.83 GABRA1 (0.44) GABRA1LMNACYP1A2CYP3A4GABRG2
SCHEMBL9967747 0.83 GABRA1 (0.44) GABRA1LMNACYP1A2CYP3A4GABRG2
SCHEMBL10591236 0.83 GABRA1 (0.44) GABRA1LMNACYP1A2CYP3A4GABRG2
SCHEMBL21893895 0.83 GABRA1 (0.60) GABRA1LMNACYP1A2CYP3A4GABRG2
SCHEMBL3794555 0.83 CYP3A4 (0.47) GABRA1LMNACYP1A2CYP3A4GABRG2
SCHEMBL16958189 0.82 LMNA (0.40) GABRA1LMNACYP1A2CYP3A4GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106892945-A A kind of N-heterocyclic carbine-palladium complex, its preparation method and application 温州大学 2017-06-27 CN claimed
CN-118146118-B Method for increasing the yield of isocyanate and method for producing isocyanate 万华化学集团股份有限公司 2026-05-19 CN disclosed
CN-120137139-A Bis (1-isocyanato-1-methylethyl) benzene composition and preparation method and application thereof 万华化学集团股份有限公司 2025-06-13 CN disclosed
CN-120081762-A Tetramethyl room xylylene group method for synthesizing dicarbamate 湖南方锐达科技有限公司 2025-06-03 CN disclosed
CN-113861041-B Compound and application thereof 北京鼎材科技有限公司 2024-07-09 CN disclosed
CN-118146118-A Method for increasing the yield of isocyanate and method for producing isocyanate 万华化学集团股份有限公司 2024-06-07 CN disclosed
US-20240016942-A1 STAT DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2024-01-18 US disclosed
US-20240016942-A1 STAT DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2024-01-18 US disclosed
US-11746120-B2 Stat degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2023-09-05 US disclosed
US-11746120-B2 Stat degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2023-09-05 US disclosed
US-20160122323-A1 INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) DANA-FARBER CANCER INSTITUTE, INC. (US) 2016-05-05 US disclosed
US-20150133491-A1 COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY CHIESI FARMACEUTICI S.P.A. (IT) 2015-05-14 US disclosed
US-8987299-B2 Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity CHIESI FARMACEUTICI S.P.A. (IT) 2015-03-24 US disclosed
US-20140161736-A1 COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY CHIESI FARMACEUTICI S.P.A (IT) 2014-06-12 US disclosed
CN-102432411-A Nitrogen-heterocyclic-cabbeen-palladium-iminazole complex for catalyzing application of aryl chloride in amination reaction UNIV WENZHOU 2012-05-02 CN disclosed
US-20110230680-A1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-09-22 US disclosed
US-7977286-B2 Substituted N,N'-diaryl-m-phenylenediamines impart good levels of oxidation inhibition in lubricants, hydraulic fluids; lubricant is a synthetic oil derived from a Fischer-Tropsch wax via palladium/phosphine complex coupling catalyst; engine, industrial, marine, hydraulic, aviation, driveline oils EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-07-12 US disclosed
EP-2029706-A2 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES ExxonMobil Research and Engineering Company (US) 2009-03-04 EP disclosed
WO-2007133462-A2 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-11-22 WO disclosed
US-20070265178-A1 Lubricating compositions containing ashless catalytic antioxidant additives EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2007-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11746120-B2 Stat degraders and uses thereof STAT4, STAT1, STAT3 GABRA1 2966/4885LMNA 4438/4885CYP1A2 486/4885
US-20160122323-A1 INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) CDK7, CDK9, CDK6 GABRA1 4407/4885LMNA 1932/4885CYP1A2 1410/4885
US-20240016942-A1 STAT DEGRADERS AND USES THEREOF STAT4, STAT1, STAT3 GABRA1 2966/4885LMNA 4438/4885CYP1A2 486/4885
US-20070265178-A1 Lubricating compositions containing ashless catalytic antioxidant additives GPX4, SOD1, GPX1 GABRA1 4834/4885LMNA 3619/4885CYP1A2 1365/4885
US-20140161736-A1 COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY ADRB2, ADRB1, ADRA2B GABRA1 113/4885LMNA 2681/4885CYP1A2 303/4885
US-20150133491-A1 COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY ADRB2, ADRB1, ADRA2B GABRA1 113/4885LMNA 2681/4885CYP1A2 303/4885
US-20110230680-A1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES GPX4, SOD1, GPX1 GABRA1 4828/4885LMNA 3636/4885CYP1A2 1221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.