Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124755 | 0.87 | KDM4E (0.48) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL3420814 | 0.85 | HTR1A (0.45) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL22048825 | 0.85 | RAB9A (0.38) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL22062297 | 0.85 | PLK4 (0.46) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL533320 | 0.85 | KDM4E (0.46) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL8205463 | 0.81 | MAPK1 (0.60) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL22062300 | 0.74 | PLK4 (0.38) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL5384431 | 0.73 | NPC1 (0.38) | MAPTKDM4EALDH1A1LMNAPLK4 | |
| SCHEMBL532721 | 0.73 | NPC1 (0.38) | MAPTKDM4EALDH1A1LMNAPLK4 | |
| SCHEMBL5388939 | 0.73 | RAB9A (0.41) | MAPTKDM4EALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11320376-B2 | Duplex stabilizing fluorescence quenchers for nucleic acid probes | ELITECHGROUP MDX LLC (US) | 2022-05-03 | — | — | US | disclosed |
| US-20210041360-A1 | DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | ELITECHGROUP, INC. (US) | 2021-02-11 | — | — | US | disclosed |
| US-10890529-B2 | Duplex stabilizing fluorescence quenchers for nucleic acid probes | ELITECHGROUP, INC. (US) | 2021-01-12 | — | — | US | disclosed |
| US-10677728-B2 | Duplex stabilizing fluorescence quenchers for nucleic acid probes | ELITECHGROUP B.V. (NL) | 2020-06-09 | — | — | US | disclosed |
| US-20200173924-A1 | DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | ELITECHGROUP, INC. (US) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10677728-B2 | Duplex stabilizing fluorescence quenchers for nucleic acid probes | DDB1, DUT, DCLRE1B | MAPT 4249/4885KDM4E 3827/4885ALDH1A1 1848/4885 |
| US-20200173924-A1 | DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | DDB1, DUT, DCLRE1B | MAPT 4249/4885KDM4E 3827/4885ALDH1A1 1848/4885 |
| US-10890529-B2 | Duplex stabilizing fluorescence quenchers for nucleic acid probes | DDB1, DUT, DCLRE1B | MAPT 4249/4885KDM4E 3827/4885ALDH1A1 1848/4885 |
| US-11320376-B2 | Duplex stabilizing fluorescence quenchers for nucleic acid probes | DDB1, DUT, DCLRE1B | MAPT 4249/4885KDM4E 3827/4885ALDH1A1 1848/4885 |
| US-20210041360-A1 | DUPLEX STABILIZING FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | DDB1, DUT, DCLRE1B | MAPT 4249/4885KDM4E 3827/4885ALDH1A1 1848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.