Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124755 | 0.87 | KDM4E (0.48) | MAPTKDM4EALDH1A1LMNAMAPKAPK2 | |
| SCHEMBL22048826 | 0.85 | MAPT (0.46) | MAPTKDM4EALDH1A1LMNAMAPKAPK2 | |
| SCHEMBL889790 | 0.83 | PLK4 (0.41) | MAPTKDM4EALDH1A1LMNAMAPKAPK2 | |
| SCHEMBL22062297 | 0.82 | PLK4 (0.46) | HTR1ADRD2MAPTKDM4EALDH1A1 | |
| SCHEMBL533320 | 0.82 | KDM4E (0.46) | MAPTKDM4EALDH1A1LMNAMAPKAPK2 | |
| SCHEMBL8205463 | 0.79 | MAPK1 (0.60) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL532721 | 0.73 | NPC1 (0.38) | MAPTKDM4EALDH1A1LMNAMAPKAPK2 | |
| SCHEMBL5384431 | 0.73 | NPC1 (0.38) | MAPTKDM4EALDH1A1LMNAMAPKAPK2 | |
| SCHEMBL13497870 | 0.73 | ALDH1A1 (0.48) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL22048825 | 0.72 | RAB9A (0.38) | MAPTKDM4EALDH1A1LMNAMAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687609-B1 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | EPOCH BIOSCIENCES INC (US) | 2014-12-10 | — | — | EP | disclosed |
| US-7759126-B2 | Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for amplification (or PCR) analysis | ELITECH HOLDING B.V. (NL) | 2010-07-20 | — | — | US | disclosed |
| US-20090111100-A1 | MINOR GROOVE BINDER - ENERGY TRANSFER OLIGONUCLEOTIDES AND METHODS FOR THEIR USE | ELITECH HOLDING B.V. (NL) | 2009-04-30 | — | — | US | disclosed |
| US-20090048439-A1 | Isolation of nucleic acids molecules using modified solid supports | ELITECH HOLDING B.V. (NL) | 2009-02-19 | — | — | US | disclosed |
| US-20080293586-A1 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | EPOCH BIOSCIENCES, INC. (US) | 2008-11-27 | — | — | US | disclosed |
| US-7381818-B2 | Fluorescent probes containing 5′-minor groove binder, fluorophore and quenching moieties and methods of use thereof | EPOCH BIOSCIENCES, INC. (US) | 2008-06-03 | — | — | US | disclosed |
| US-20050214797-A1 | Fluorescent probes for DNA detection by hybridization with improved sensitivity and low background | EPOCH BIOSCIENCES, INC (US) | 2005-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048439-A1 | Isolation of nucleic acids molecules using modified solid supports | POLRMT, SSU72, MRPS27 | HTR1A 3988/4885DRD2 4119/4885MAPT 3438/4885 |
| US-20080293586-A1 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | SSBP1, DDB1, DNA2 | HTR1A 3846/4885DRD2 4333/4885MAPT 3770/4885 |
| US-20090111100-A1 | MINOR GROOVE BINDER - ENERGY TRANSFER OLIGONUCLEOTIDES AND METHODS FOR THEIR USE | SSBP1, SNRPE, TARBP1 | HTR1A 4559/4885DRD2 4479/4885MAPT 3011/4885 |
| US-20050214797-A1 | Fluorescent probes for DNA detection by hybridization with improved sensitivity and low background | SSBP1, DDB1, DNA2 | HTR1A 3846/4885DRD2 4333/4885MAPT 3770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.