Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5388939 | 0.86 | RAB9A (0.41) | KDM4EALDH1A1MAPTHPGDMTNR1A | |
| SCHEMBL8205463 | 0.86 | MAPK1 (0.60) | KDM4EALDH1A1MAPTHPGDPLK4 | |
| SCHEMBL22048826 | 0.85 | MAPT (0.46) | KDM4EALDH1A1MAPTHPGDMTNR1A | |
| SCHEMBL124755 | 0.83 | KDM4E (0.48) | KDM4EALDH1A1MAPTHPGDMTNR1A | |
| SCHEMBL3420814 | 0.82 | HTR1A (0.45) | KDM4EALDH1A1MAPTHPGDMTNR1A | |
| SCHEMBL22062297 | 0.81 | PLK4 (0.46) | KDM4EALDH1A1MAPTHPGDMTNR1A | |
| SCHEMBL889790 | 0.80 | PLK4 (0.41) | KDM4EALDH1A1MAPTHPGDMTNR1A | |
| SCHEMBL888365 | 0.78 | CYP1A2 (0.41) | KDM4EALDH1A1MAPTHPGDMTNR1A | |
| SCHEMBL25507489 | 0.78 | XDH (0.44) | MAPTMAPK1LMNACYP1A2XDH | |
| SCHEMBL19332290 | 0.77 | MAPT (0.45) | KDM4EALDH1A1MAPTMAPKAPK2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121667-B1 | CHEMICAL LINKERS WITH SINGLE AMINO ACIDS AND CONJUGATES THEREOF | SQUIBB & SONS LLC (US) | 2016-06-08 | — | — | EP | disclosed |
| EP-2121667-B1 | CHEMICAL LINKERS WITH SINGLE AMINO ACIDS AND CONJUGATES THEREOF | SQUIBB & SONS LLC (US) | 2016-06-08 | — | — | EP | disclosed |
| EP-1687609-B1 | FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND | EPOCH BIOSCIENCES INC (US) | 2014-12-10 | — | — | EP | disclosed |
| US-8664407-B2 | Chemical linkers with single amino acids and conjugates thereof | Medarex, LLC (US) | 2014-03-04 | — | — | US | disclosed |
| US-8664407-B2 | Chemical linkers with single amino acids and conjugates thereof | Medarex, LLC (US) | 2014-03-04 | — | — | US | disclosed |
| US-8664407-B2 | Chemical linkers with single amino acids and conjugates thereof | Medarex, LLC (US) | 2014-03-04 | — | — | US | disclosed |
| US-8465921-B2 | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders | ELITECH HOLDING B.V. (NL) | 2013-06-18 | — | — | US | disclosed |
| US-8461117-B2 | Chemical linkers and cleavable substrates and conjugates thereof | MEDAREX, INC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-8461117-B2 | Chemical linkers and cleavable substrates and conjugates thereof | MEDAREX, INC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-8461117-B2 | Chemical linkers and cleavable substrates and conjugates thereof | MEDAREX, INC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-20030096254-A1 | Enhancing resonance ability of oligonuclotide probes for use in hybridization assays; gene expression | EPOCH BIOSCIENCES, INC. (US) | 2003-05-22 | — | — | US | disclosed |
| US-20030008304-A1 | Fluorescent quenching detection reagents and methods | EPOCH BIOSCIENCES, INC. (US) | 2003-01-09 | — | — | US | disclosed |
| WO-2002099141-A1 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES, INC. (US) | 2002-12-12 | — | — | WO | disclosed |
| US-6472153-B1 | COVALENTLY BOUND OLIGONUCLEOTIDE/MINOR GROOVE BINDER/LATENT FLUOROPHORE COMBINATION | EPOCH BIOSCIENCES, INC. | 2002-10-29 | — | — | US | disclosed |
| US-20020155484-A1 | Fluorescent quenching detection reagents and methods | EPOCH PHARMACEUTICALS, INC. (US) | 2002-10-24 | — | — | US | disclosed |
| EP-1235938-A2 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | Epoch Biosciences, Inc. (US) | 2002-09-04 | — | — | EP | disclosed |
| EP-1224332-A1 | HYBRIDIZATION-TRIGGERED FLUORESCENT DETECTION OF NUCLEIC ACIDS | Epoch Biosciences, Inc. (US) | 2002-07-24 | — | — | EP | disclosed |
| US-20020034754-A1 | Fluorescent quenching detection reagents and methods | ELITECHGROUP, INC. | 2002-03-21 | — | — | US | disclosed |
| WO-2001042505-A2 | FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS | EPOCH BIOSCIENCES, INC. (US) | 2001-06-14 | — | — | WO | disclosed |
| WO-2001031063-A1 | HYBRIDIZATION-TRIGGERED FLUORESCENT DETECTION OF NUCLEIC ACIDS | EPOCH BIOSCIENCES, INC. (US) | 2001-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008304-A1 | Fluorescent quenching detection reagents and methods | DDX5, DDX21, DCLRE1B | KDM4E 4634/4885ALDH1A1 2350/4885MAPT 4772/4885 |
| US-20020034754-A1 | Fluorescent quenching detection reagents and methods | DDX5, DDX21, DCLRE1B | KDM4E 4634/4885ALDH1A1 2350/4885MAPT 4772/4885 |
| US-20020155484-A1 | Fluorescent quenching detection reagents and methods | IPO4, PTBP3, DDX5 | KDM4E 3864/4885ALDH1A1 3183/4885MAPT 4738/4885 |
| US-20030096254-A1 | Enhancing resonance ability of oligonuclotide probes for use in hybridization assays; gene expression | DCLRE1B, SNRPE, ZFR | KDM4E 4757/4885ALDH1A1 2641/4885MAPT 4863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.