Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ADAMTS7 | Q9UKP4 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23877960 | 0.81 | HSD11B1 (0.43) | HSD11B1ACLYMGLLS1PR5PTPN1 | |
| SCHEMBL13774624 | 0.76 | HSD11B1 (0.71) | HSD11B1ACLYPTPN1RAB9AKMT2A | |
| SCHEMBL24212006 | 0.69 | S1PR5 (0.43) | MGLLS1PR5RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL22050849 | 0.66 | KIF11 (0.42) | MGLLS1PR5RAB9ASMN1; SMN2CNR2 | |
| SCHEMBL13774627 | 0.65 | PTPN1 (0.63) | S1PR5PTPN1KMT2AALDH1A1 | |
| SCHEMBL29784281 | 0.65 | RXRA (0.72) | PTPN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL2344585 | 0.65 | RXRA (0.72) | PTPN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL22050486 | 0.65 | USP5 (0.51) | S1PR5ADAMTS7ADAMTS5KMT2AALDH1A1 | |
| SCHEMBL22051935 | 0.65 | USP5 (0.51) | S1PR5ADAMTS7ADAMTS5KMT2AALDH1A1 | |
| SCHEMBL18054903 | 0.64 | ALDH1A1 (0.45) | S1PR5SMN1; SMN2ALDH1A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020111252-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | 国立大学法人九州大学 | 2020-06-04 | — | — | WO | disclosed |