Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | PLAT | P00750 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23877960 | 0.80 | HSD11B1 (0.43) | S1PR5KMT2ASMN1; SMN2RAB9AMGLL | |
| SCHEMBL22050849 | 0.77 | KIF11 (0.42) | S1PR5KIF11SMN1; SMN2RAB9ASLC6A7 | |
| SCHEMBL18054903 | 0.72 | ALDH1A1 (0.45) | S1PR5KIF11SMN1; SMN2SLC6A7GRIN2B | |
| SCHEMBL13774627 | 0.72 | PTPN1 (0.63) | S1PR5KMT2AKIF11SLC6A7PLG | |
| SCHEMBL21758282 | 0.71 | KIF11 (0.53) | S1PR5KIF11SLC6A7PLGPLAU | |
| SCHEMBL2984165 | 0.70 | KIF11 (0.58) | S1PR5KMT2AKIF11SMN1; SMN2SLC6A7 | |
| SCHEMBL22051364 | 0.69 | HSD11B1 (0.42) | S1PR5KMT2ASMN1; SMN2RAB9AMGLL | |
| SCHEMBL2344585 | 0.68 | RXRA (0.72) | KMT2AKIF11RAB9APLGPLAU | |
| SCHEMBL29784281 | 0.68 | RXRA (0.72) | KMT2AKIF11RAB9APLGPLAU | |
| SCHEMBL22051970 | 0.68 | KIF11 (0.40) | S1PR5KMT2AKIF11SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017486-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2022-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220017486-A1 | DOCK1-INHIBITING COMPOUND AND USE THEREOF | DOCK2, DOCK11, DOCK5 | S1PR5 4787/4885KMT2A 1929/4885GHSR 1023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.