SCHEMBL22068902

SCHEMBL22068902

CCSc1ccc(Oc2ccc(Sc3ccc(Oc4ccc(S)cc4)cc3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
SLC6A4 P31645 9/20 0.36
MAOA P21397 1/20 0.36
LTA4H P09960 3/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
STS P08842 1/20 0.32
PTGIR P43119 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22068903 0.94 ALDH1A1 (0.44) ALDH1A1SLC6A4MAOALTA4HNPC1
SCHEMBL8372191 0.82 SLC6A4 (0.47) ALDH1A1SLC6A4MAOANPC1RAB9A
SCHEMBL10316183 0.78 SLC6A4 (0.50) SLC6A4MAOANPC1RAB9A
SCHEMBL1127464 0.77 LTA4H (0.44) ALDH1A1SLC6A4MAOALTA4HSTS
SCHEMBL18892562 0.77 ALDH1A1 (0.46) ALDH1A1SLC6A4MAOA
SCHEMBL13969406 0.77 LTA4H (0.55) ALDH1A1MAOALTA4HNPC1RAB9A
SCHEMBL10525886 0.77 SLC6A4 (0.43) SLC6A4MAOANPC1RAB9A
SCHEMBL3947933 0.73 CA2 (0.41) ALDH1A1SLC6A4MAOANPC1RAB9A
SCHEMBL9501765 0.73 SLC6A4 (0.44) ALDH1A1SLC6A4MAOALTA4HNPC1
SCHEMBL9474265 0.73 ST14 (0.57) ALDH1A1SLC6A4MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3438092-B1 METHOD FOR PREPARING COMPOUND AND METHOD FOR PREPARING POLYMER EMPLOYING THE SAME IND TECH RES INST (TW) 2020-06-17 EP disclosed