SCHEMBL22079752

SCHEMBL22079752

COc1cc(C(C)(C)C)c(C)c2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
HPGD P15428 2/20 0.43
ALOX15 P16050 2/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
IDO1 P14902 1/20 0.40
EP300 Q09472 2/20 0.39
KAT8 Q9H7Z6 1/20 0.39
NQO1 P15559 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HTR2A P28223 1/20 0.38
ATM Q13315 2/20 0.37
IMPDH2 P12268 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22857618 0.84 NQO1 (0.56) LMNAHPGDALOX15TP53CYP3A4
SCHEMBL23463350 0.83 ATM (0.37) LMNAHPGDIDO1EP300KAT8
SCHEMBL9967886 0.81 SMN1; SMN2 (0.50) LMNAHPGDALOX15TP53CYP3A4
SCHEMBL22079757 0.81 CYP1A2 (0.36) HPGDIDO1MAPTALDH1A1
SCHEMBL8762756 0.80 TP53 (0.50) LMNAHPGDALOX15TP53CYP3A4
SCHEMBL3972592 0.78 IDO1 (0.47) LMNAHPGDALOX15IDO1EP300
SCHEMBL23763396 0.76 CYP1A2 (0.44) LMNAHPGDALOX15CA2MAPT
SCHEMBL11887380 0.76 IDO1 (0.45) LMNAHPGDIDO1EP300KAT8
SCHEMBL8253573 0.75 IDO1 (0.53) LMNAHPGDIDO1EP300KAT8
SCHEMBL13714134 0.73 IDO1 (0.42) LMNAHPGDIDO1EP300KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11820783-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-21 US disclosed
US-11820783-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-21 US disclosed
US-20230348510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-20230348510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-20230337523-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-11739081-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-29 US disclosed
US-11739081-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-29 US disclosed
US-20230269999-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-08-24 US disclosed
US-20230257407-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-08-17 US disclosed
US-20230257407-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-08-17 US disclosed
US-20210047354-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-02-18 US disclosed
US-20210050529-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-02-18 US disclosed
US-20210024556-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-01-28 US disclosed
US-20210002311-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-01-07 US disclosed
US-20200358008-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-12 US disclosed
US-20200350502-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-05 US disclosed
US-20200331941-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-10-22 US disclosed
US-20200325125-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-10-15 US disclosed
US-20200291006-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-09-17 US disclosed
US-20200181182-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200325125-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, LOXL1, OCIAD2 LMNA 576/4885HPGD 597/4885ALOX15 20/4885
US-20200350502-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OSBPL3, OSBP2 LMNA 1536/4885HPGD 2086/4885ALOX15 96/4885
US-11739081-B2 Organic electroluminescent materials and devices ICMT, KCNQ2, KCNQ1 LMNA 1026/4885HPGD 3011/4885ALOX15 2458/4885
US-11820783-B2 Organic electroluminescent materials and devices LOXL1, ILK, SOD1 LMNA 220/4885HPGD 3321/4885ALOX15 680/4885
US-20200291006-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICMT, KCNQ2, KCNQ1 LMNA 1026/4885HPGD 3011/4885ALOX15 2458/4885
US-20230257407-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES IK, ORC3, REL LMNA 2421/4885HPGD 3485/4885ALOX15 2657/4885
US-20230337523-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OCIAD1, OCIAD2 LMNA 812/4885HPGD 2907/4885ALOX15 602/4885
US-20210002311-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OTC LMNA 3061/4885HPGD 855/4885ALOX15 516/4885
US-20230269999-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ACAT1, ACMSD, SLC25A21 LMNA 3539/4885HPGD 316/4885ALOX15 232/4885
US-20200181182-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ICOSLG LMNA 2348/4885HPGD 2016/4885ALOX15 50/4885
US-20200358008-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EPCAM, SOD1 LMNA 685/4885HPGD 3724/4885ALOX15 2278/4885
US-20200331941-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LEF1, L1CAM, SSB LMNA 552/4885HPGD 4688/4885ALOX15 1755/4885
US-20210024556-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES IK, ORC3, REL LMNA 2421/4885HPGD 3485/4885ALOX15 2657/4885
US-20230348510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OXER1, OXSR1 LMNA 548/4885HPGD 3705/4885ALOX15 1628/4885
US-20210047354-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, LEF1, EPCAM LMNA 521/4885HPGD 2979/4885ALOX15 237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.