Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21805979 | 0.84 | ATM (0.44) | ALDH1A1KMT2ALMNASMN1; SMN2CYP2C19 | |
| SCHEMBL2254362 | 0.84 | OPRM1 (0.56) | KMT2ASMN1; SMN2MEN1OPRM1 | |
| SCHEMBL2252823 | 0.83 | OPRM1 (0.56) | SMN1; SMN2OPRM1 | |
| SCHEMBL20500624 | 0.81 | PPARA (0.39) | ALDH1A1LMNAPOLBCYP2C19OPRM1 | |
| SCHEMBL28318807 | 0.80 | OPRM1 (0.57) | LMNASMN1; SMN2NPSR1TDP1CHRM2 | |
| SCHEMBL22027277 | 0.80 | DGAT1 (0.46) | KMT2ALMNASMN1; SMN2HSD11B1CYP2C19 | |
| SCHEMBL2254427 | 0.76 | LIPG (0.40) | OPRM1 | |
| SCHEMBL22027167 | 0.76 | PLK1 (0.45) | ALDH1A1KMT2ALMNASMN1; SMN2POLB | |
| SCHEMBL22026919 | 0.76 | NAAA (0.46) | ALDH1A1LMNASMN1; SMN2HSD11B1CYP2C19 | |
| SCHEMBL26791021 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KMT2ALMNASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002309-A1 | SSAO INHIBITORS AND USES THEREOF | METACRINE, INC. | 2022-01-06 | — | — | US | disclosed |
| US-20200181104-A1 | SSAO INHIBITORS AND USES THEREOF | METACRINE, INC. | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002309-A1 | SSAO INHIBITORS AND USES THEREOF | AOX1, AOC2, MAOA | ALDH1A1 58/4885KMT2A 3212/4885LMNA 1461/4885 |
| US-20200181104-A1 | SSAO INHIBITORS AND USES THEREOF | AOX1, AOC2, MAOA | ALDH1A1 58/4885KMT2A 3212/4885LMNA 1461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.