Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL225085 | 0.84 | KMT2A (0.65) | KMT2AMEN1 | |
| SCHEMBL4827698 | 0.84 | KMT2A (0.48) | KMT2AMEN1HPGDKMODHFR | |
| SCHEMBL14422348 | 0.84 | ALDH1A1 (0.51) | KMT2AMEN1HPGDSLC6A3 | |
| SCHEMBL1531846 | 0.81 | MEN1 (0.61) | KMT2AMEN1 | |
| SCHEMBL224697 | 0.80 | RAB9A (0.44) | KMT2AMEN1CREBBPHPGD | |
| SCHEMBL5727243 | 0.77 | PKM (0.46) | KMT2AMEN1DHFR | |
| SCHEMBL14281436 | 0.77 | KMT2A (0.67) | KMT2AMEN1CREBBPEP300PLA2G2A | |
| SCHEMBL3868693 | 0.77 | KMT2A (0.36) | KMT2AMEN1HPGDDHFRPTPN1 | |
| SCHEMBL13577642 | 0.77 | DHFR (0.38) | KMT2AMEN1DHFRPTPN1 | |
| SCHEMBL18868394 | 0.76 | ALDH1A1 (0.47) | KMT2AMEN1HPGDSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9719018-B2 | Monomer, liquid crystal composition, liquid crystal display device, and production method for liquid crystal display device | SHARP KABUSHIKI KAISHA (JP) | 2017-08-01 | — | — | US | disclosed |
| US-9719018-B2 | Monomer, liquid crystal composition, liquid crystal display device, and production method for liquid crystal display device | SHARP KABUSHIKI KAISHA (JP) | 2017-08-01 | — | — | US | disclosed |
| US-9719018-B2 | Monomer, liquid crystal composition, liquid crystal display device, and production method for liquid crystal display device | SHARP KABUSHIKI KAISHA (JP) | 2017-08-01 | — | — | US | disclosed |
| US-20150247090-A1 | MONOMER, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY DEVICE, AND PRODUCTION METHOD FOR LIQUID CRYSTAL DISPLAY DEVICE | SHARP KABUSHIKI KAISHA (JP) | 2015-09-03 | — | — | US | disclosed |
| US-20150247090-A1 | MONOMER, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY DEVICE, AND PRODUCTION METHOD FOR LIQUID CRYSTAL DISPLAY DEVICE | SHARP KABUSHIKI KAISHA (JP) | 2015-09-03 | — | — | US | disclosed |
| US-20150247090-A1 | MONOMER, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY DEVICE, AND PRODUCTION METHOD FOR LIQUID CRYSTAL DISPLAY DEVICE | SHARP KABUSHIKI KAISHA (JP) | 2015-09-03 | — | — | US | disclosed |
| WO-2013022605-A1 | MESOGENIC STABILIZERS | TRANSITIONS OPTICAL, INC. (US) | 2013-02-14 | — | — | WO | disclosed |
| US-8349210-B2 | Mesogenic stabilizers | TRANSITIONS OPTICAL, INC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-20120003401-A1 | MESOGENIC STABILIZERS | TRANSITIONS OPTICAL, INC. (US) | 2012-01-05 | — | — | US | disclosed |
| US-7491741-B2 | Diaminopropionic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 2009-02-17 | — | — | US | disclosed |
| US-20050080119-A1 | Diaminopropionic acid derivatives | FOTOUHI NADER (US) | 2005-04-14 | — | — | US | disclosed |
| US-6803384-B2 | FOR THERAPY OF REPERFUSION INJURY | HOFFMANN-LA ROCHE INC. | 2004-10-12 | — | — | US | disclosed |
| US-6716948-B1 | POLYFUNCTIONAL NITROXIDE INITIATORS; MULTIPLE FREE RADICAL ACRYLAMIDE LIVING POLYMERIZATION; STAR POLYMERS; REPLACEABLE CAPILLARY ELECTROPHORESIS SEPARATION MEDIA FOR BIOLOGICAL MOLECULES SUCH AS DNA | SYMYX TECHNOLOGIES, INC. | 2004-04-06 | — | — | US | disclosed |
| US-20040006236-A1 | Diaminopropionic acid derivatives | FOTOUHI NADER (US) | 2004-01-08 | — | — | US | disclosed |
| WO-2001009204-A9 | CONTROLLED-ARCHITECTURE POLYMERS AND USE THEREOF AS SEPARATION MEDIA | SYMYX TECHNOLOGIES INC (US) | 2002-09-26 | — | — | WO | disclosed |
| US-20020052512-A1 | Diaminopropionic acid derivatives | FOTOUHI NADER (US) | 2002-05-02 | — | — | US | disclosed |
| US-6331640-B1 | TREATMENT OF REPERFUSION INJURIES | HOFFMANN-LA ROCHE INC. | 2001-12-18 | — | — | US | disclosed |
| EP-1121342-A1 | DIAMINOPROPIONIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-08-08 | — | — | EP | disclosed |
| WO-2001009204-A2 | CONTROLLED-ARCHITECTURE POLYMERS AND USE THEREOF AS SEPARATION MEDIA | SYMYX TECHNOLOGIES, INC. (US) | 2001-02-08 | — | — | WO | disclosed |
| WO-2000021920-A1 | DIAMINOPROPIONIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120003401-A1 | MESOGENIC STABILIZERS | PYM1, BMI1, C1S | KMT2A 375/4885MEN1 17/4885CREBBP 3177/4885 |
| US-20150247090-A1 | MONOMER, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY DEVICE, AND PRODUCTION METHOD FOR LIQUID CRYSTAL DISPLAY DEVICE | NLRP1, PYCARD, NLRP3 | KMT2A 2215/4885MEN1 2550/4885CREBBP 3804/4885 |
| US-20040006236-A1 | Diaminopropionic acid derivatives | AIFM1, AIFM2, HIF1A | KMT2A 3790/4885MEN1 4444/4885CREBBP 1846/4885 |
| US-20020052512-A1 | Diaminopropionic acid derivatives | AIFM1, AIFM2, HIF1A | KMT2A 3790/4885MEN1 4444/4885CREBBP 1846/4885 |
| US-20050080119-A1 | Diaminopropionic acid derivatives | AIFM1, HIF1A, AIFM2 | KMT2A 4000/4885MEN1 4739/4885CREBBP 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.