SCHEMBL22118513

SCHEMBL22118513

CC(C)(C)c1cc(-c2c(C(C)(C)C)c(C(C)(C)C)cc3cc4ccccc4cc23)cc(C(C)(C)C)c1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ RXRA P19793 2/20 0.32
▸ RXRB P28702 2/20 0.32
▸ MEN1 O00255 2/20 0.31
▸ KMT2A Q03164 2/20 0.31
▸ NPC1 O15118 1/20 0.31
▸ RXRG P48443 1/20 0.31
▸ GPR84 Q9NQS5 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.30
▸ POLB P06746 1/20 0.30
▸ NPSR1 Q6W5P4 1/20 0.30
▸ S1PR1 P21453 1/20 0.30
▸ S1PR3 Q99500 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6135773 0.84 ESR1 (0.39) MEN1KMT2AALDH1A1
SCHEMBL25193124 0.77 GPR84 (0.34) KDM4EGAAMAPTRXRARXRB
SCHEMBL11377784 0.77 NQO1 (0.36) KDM4EGAAMAPTALDH1A1
SCHEMBL22411205 0.72 NQO1 (0.33) ALDH1A1
SCHEMBL5335957 0.70 GSTP1 (0.42) KDM4EGPR84
SCHEMBL9651812 0.69 CA2 (0.41) GAAMAPTMEN1KMT2AALDH1A1
SCHEMBL5010176 0.69 NQO1 (0.39) KDM4EGAAMAPTNPC1ALDH1A1
SCHEMBL26965728 0.69 ESR1 (0.40) NPC1GPR84ALDH1A1
SCHEMBL22142542 0.68 GAA (0.39) KDM4EGAAMAPTRXRARXRB
SCHEMBL3420318 0.68 ALDH1A1 (0.40) KDM4EGAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12297311-B2 Biaryl hydroxythiophene group IV transition metal polymerization with chain transfer capability DOW GLOBAL TECHNOLOGIES LLC (US) 2025-05-13 — — US disclosed
US-20250051495-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A SILOCON BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLYETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR DOW GLOBAL TECHNOLOGIES LLC (US) 2025-02-13 — — US disclosed
US-20250034292-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A GERMANIUM BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLYETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR DOW GLOBAL TECHNOLOGIES LLC (US) 2025-01-30 — — US disclosed
US-20250011478-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A CARBON BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLYETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR DOW GLOBAL TECHNOLOGIES LLC (US) 2025-01-09 — — US disclosed
US-12122862-B2 Biaryl hydroxythiophene group IV transition metal polymerization catalysts with chain transfer capability DOW GLOBAL TECHNOLOGIES LLC (US) 2024-10-22 — — US disclosed
EP-4437012-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A CARBON BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLY ETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR Dow Global Technologies LLC (US) 2024-10-02 — — EP disclosed
EP-4437011-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A GERMANIUM BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLYETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR Dow Global Technologies LLC (US) 2024-10-02 — — EP disclosed
EP-4437013-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A SILOCON BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLYETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR Dow Global Technologies LLC (US) 2024-10-02 — — EP disclosed
CN-118302456-A Supported catalyst system containing germanium bridged, anthracenyl substituted bis-biphenyl-phenoxy organometallic compounds for preparing polyethylene and polyethylene copolymer resins in a gas phase polymerization reactor 陶氏环球技术有限责任公司 2024-07-05 — — CN disclosed
CN-118302457-A Supported catalyst system containing carbon-bridged, anthracenyl-substituted bis-biphenyl-phenoxy organometallic compounds for preparing polyethylene and polyethylene copolymer resins in a gas phase polymerization reactor 陶氏环球技术有限责任公司 2024-07-05 — — CN disclosed
WO-2023096865-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A SILOCON BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLYETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-01 — — WO disclosed
WO-2023096868-A1 SUPPORTED CATALYST SYSTEMS CONTAINING A GERMANIUM BRIDGED, ANTHRACENYL SUBSTITUTED BIS-BIPHENYL-PHENOXY ORGANOMETALLIC COMPOUND FOR MAKING POLYETHYLENE AND POLYETHYLENE COPOLYMER RESINS IN A GAS PHASE POLYMERIZATION REACTOR DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-01 — — WO disclosed
US-20220169756-A1 BIARYL HYDROXYTHIOPHENE GROUP IV TRANSITION METAL POLYMERIZATION WITH CHAIN TRANSFER CAPABILITY DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-02 — — US disclosed
US-20220025085-A1 BIARYL HYDROXYTHIOPHENE GROUP IV TRANSITION METAL POLYMERIZATION CATALYSTS WITH CHAIN TRANSFER CAPABILITY DOW GLOBAL TECHNOLOGIES LLC (US) 2022-01-27 — — US disclosed
EP-3935091-A1 BIARYL HYDROXYTHIOPHENE GROUP IV TRANSITION METAL POLYMERIZATION WITH CHAIN TRANSFER CAPABILITY Dow Global Technologies LLC (US) 2022-01-12 — — EP disclosed
CN-113748138-A Biaryl hydroxythiophene group IV transition metal polymerization with chain transfer capability 陶氏环球技术有限责任公司 2021-12-03 — — CN disclosed
EP-3898724-A1 BIARYL HYDROXYTHIOPHENE GROUP IV TRANSITION METAL POLYMERIZATION CATALYSTS WITH CHAIN TRANSFER CAPABILITY Dow Global Technologies LLC (US) 2021-10-27 — — EP disclosed
CN-113348186-A Biaryl hydroxy thiophene IV group transition metal polymerization catalyst with chain transfer capability 陶氏环球技术有限责任公司 2021-09-03 — — CN disclosed
WO-2020185494-A1 BIARYL HYDROXYTHIOPHENE GROUP IV TRANSITION METAL POLYMERIZATION WITH CHAIN TRANSFER CAPABILITY DOW GLOBAL TECHNOLOGIES LLC (US) 2020-09-17 — — WO disclosed
WO-2020132244-A1 BIARYL HYDROXYTHIOPHENE GROUP IV TRANSITION METAL POLYMERIZATION CATALYSTS WITH CHAIN TRANSFER CAPABILITY DOW GLOBAL TECHNOLOGIES LLC (US) 2020-06-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220025085-A1 BIARYL HYDROXYTHIOPHENE GROUP IV TRANSITION METAL POLYMERIZATION CATALYSTS WITH CHAIN TRANSFER CAPABILITY TRMT1, GFPT1, BCAT1 KDM4E 3184/4885GAA 2661/4885MAPT 430/4885
US-12122862-B2 Biaryl hydroxythiophene group IV transition metal polymerization catalysts with chain transfer capability TRMT1, GFPT1, BCAT1 KDM4E 3184/4885GAA 2661/4885MAPT 430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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