Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 13/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.38 |
| ▸ | KIT | P10721 | 3/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201324 | 0.90 | ADORA3 (0.39) | ABL1TGFBR1KDM4EMEN1KMT2A | |
| SCHEMBL22201489 | 0.89 | SYK (0.37) | PRKD1TGFBR1KDM4EMEN1KMT2A | |
| SCHEMBL22201488 | 0.88 | ADORA3 (0.37) | TGFBR1KDM4EMEN1KMT2ASYK | |
| SCHEMBL22201494 | 0.88 | JAK2 (0.36) | TGFBR1KDM4ESYK | |
| SCHEMBL22201322 | 0.88 | PIP4K2C (0.34) | TGFBR1KDM4EMEN1KMT2A | |
| SCHEMBL22201326 | 0.87 | ULK1 (0.40) | ABL1TGFBR1KDM4EMEN1KMT2A | |
| SCHEMBL22201366 | 0.86 | MAPT (0.39) | ABL1KDM4EMEN1KMT2ASYK | |
| SCHEMBL22201485 | 0.86 | ULK1 (0.40) | ABL1TGFBR1KDM4EMEN1KMT2A | |
| SCHEMBL22201492 | 0.86 | P2RX3 (0.32) | PRKD1TGFBR1KDM4EMEN1KMT2A | |
| SCHEMBL22201586 | 0.86 | PRKCH (0.47) | TGFBR1KDM4EMEN1KMT2ASYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |