Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 5/20 | 0.40 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201326 | 0.93 | ULK1 (0.40) | ULK1ULK2KDM4EMEN1ALDH1A1 | |
| SCHEMBL22201494 | 0.89 | JAK2 (0.36) | ULK1ULK2KDM4ELMNACYP1A2 | |
| SCHEMBL22201489 | 0.88 | SYK (0.37) | KDM4EMEN1CYP1A2CYP3A4MAPT | |
| SCHEMBL22201488 | 0.87 | ADORA3 (0.37) | KDM4EMEN1CYP1A2KMT2AKDR | |
| SCHEMBL22201492 | 0.87 | P2RX3 (0.32) | ULK1ULK2KDM4EMEN1ALDH1A1 | |
| SCHEMBL22201536 | 0.86 | ACP1 (0.36) | ULK1ULK2CYP1A2CYP2C19ACP1 | |
| SCHEMBL22201423 | 0.86 | TRPV1 (0.41) | ULK1ULK2TRPV1 | |
| SCHEMBL22201324 | 0.86 | ADORA3 (0.39) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL22201531 | 0.86 | ABL1 (0.38) | KDM4EMEN1ALDH1A1KMT2AABL1 | |
| SCHEMBL22201366 | 0.84 | MAPT (0.39) | KDM4EMEN1ALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |