Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phenolsulfonphthalein. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS known ✓ | P04818 | 2/20 | 0.46 |
| ▸ | ESR2 known ✓ | Q92731 | 1/20 | 0.46 |
| ▸ | DHFR known ✓ | P00374 | 1/20 | 0.35 |
| ▸ | ADORA3 known ✓ | P0DMS8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.83 |
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.83 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.83 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.83 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenolsulfonphthalein SCHEMBL29368063 | 1.00 | MEN1 (0.83) | MEN1LMNAKMT2ACYP1A2CYP2C9 | |
| Phenolsulfonphthalein SCHEMBL17836 | 0.91 | MEN1 (1.00) | MEN1LMNAKMT2ACYP1A2CYP2C9 | |
| Phenolsulfonphthalein SCHEMBL29357178 | 0.91 | MEN1 (1.00) | MEN1LMNAKMT2ACYP1A2CYP2C9 | |
| Phenolsulfonphthalein SCHEMBL1157401 | 0.90 | MEN1 (0.97) | MEN1LMNAKMT2ACYP1A2CYP2C9 | |
| Phenolsulfonphthalein SCHEMBL9435992 | 0.80 | MEN1 (0.68) | MEN1LMNAKMT2ACYP1A2CYP2C9 | |
| SCHEMBL16286113 | 0.80 | MEN1 (0.76) | MEN1LMNAKMT2ACYP1A2CYP2C9 | |
| SCHEMBL16303120 | 0.79 | MEN1 (0.75) | MEN1LMNAKMT2ACYP1A2CYP2C9 | |
| SCHEMBL19697615 | 0.79 | MEN1 (0.75) | MEN1LMNAKMT2ACYP1A2CYP2C9 | |
| SCHEMBL14905228 | 0.79 | MEN1 (0.75) | MEN1LMNAKMT2ACYP1A2CYP2C9 | |
| SCHEMBL13227319 | 0.78 | MEN1 (0.75) | MEN1LMNAKMT2ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260085292-A1 | MINIMAL ESSENTIAL MEDIA FOR THE CULTURE OF HUMAN INDUCED PLURIPOTENT STEM CELLS | UNIV NORTHWESTERN (US) | 2026-03-26 | — | — | US | disclosed |
| EP-3551548-B1 | DEVICES FOR MONITORING FOOD FRESHNESS | GRANEVITZE ZUR (IL) | 2024-12-25 | — | — | EP | disclosed |
| EP-4448404-A1 | INDICATOR DEVICE AND SYSTEM AND USES THEREOF FOR DETECTING FOOD SPOILAGE | Bio Tip Ltd (IL) | 2024-10-23 | — | — | EP | disclosed |
| US-20240310348-A1 | INDICATOR DEVICE AND SYSTEM AND USES THEREOF FOR DETECTING FOOD SPOILAGE | BIO TIP LTD (IL) | 2024-09-19 | — | — | US | disclosed |
| CN-117917987-A | Loop-mediated isothermal amplification (LAMP) analysis of pathogenic targets | 普渡研究基金会 | 2024-04-23 | — | — | CN | disclosed |
| CN-117881793-A | Loop-mediated isothermal amplification (LAMP) analysis of pathogenic targets | 普渡研究基金会 | 2024-04-12 | — | — | CN | disclosed |
| EP-4278001-A1 | LOOP-MEDIATED ISOTHERMAL AMPLIFICATION (LAMP) ANALYSIS FOR PATHOGENIC TARGETS | Purdue Research Foundation (US) | 2023-11-22 | — | — | EP | disclosed |
| EP-4278000-A1 | LOOP-MEDIATED ISOTHERMAL AMPLIFICATION (LAMP) ANALYSIS FOR PATHOGENIC TARGETS | Purdue Research Foundation (US) | 2023-11-22 | — | — | EP | disclosed |
| EP-4277997-A1 | LOOP-MEDIATED ISOTHERMAL AMPLIFICATION (LAMP) ANALYSIS FOR PATHOGENIC TARGETS | Purdue Research Foundation (US) | 2023-11-22 | — | — | EP | disclosed |
| WO-2023112035-A1 | INDICATOR DEVICE AND SYSTEM AND USES THEREOF FOR DETECTING FOOD SPOILAGE | DO-BIO LTD (IL) | 2023-06-22 | — | — | WO | disclosed |
| US-6627394-B2 | Apparatus for detecting vaginal fluids for use in the diagnosis of urogenital disorders | COMMON SENSE LTD. (IL) | 2003-09-30 | — | — | US | disclosed |
| WO-2003007997-A2 | SECRETION-MONITORING ARTICLE | COMMON SENSE LTD. (IL) | 2003-01-30 | — | — | WO | disclosed |
| US-6200817-B1 | PH and amine test elements and applications to diagnosis of vaginal infections | LITMUS CONCEPTS, INC. | 2001-03-13 | — | — | US | disclosed |
| US-6113856-A | Method of making a pH and amine test element | LITMUS CONCEPTS, INC. (US) | 2000-09-05 | — | — | US | disclosed |
| US-6099801-A | pH and amine test elements and applications to diagnosis of vaginal infections | LITMUS CONCEPTS, INC. (US) | 2000-08-08 | — | — | US | disclosed |
| EP-0925501-A1 | pH AND AMINE TEST ELEMENTS AND APPLICATIONS TO DIAGNOSIS OF VAGINAL INFECTIONS | LITMUS CONCEPTS, INC. (US) | 1999-06-30 | — | — | EP | disclosed |
| US-5910447-A | pH and amine test to diagnosis of vaginal infections | LITMUS CONCEPTS, INC. (US) | 1999-06-08 | — | — | US | disclosed |
| US-5897834-A | pH test elements | LITMUS CONCEPTS, INC. (US) | 1999-04-27 | — | — | US | disclosed |
| WO-1998007027-A1 | pH AND AMINE TEST ELEMENTS AND APPLICATIONS TO DIAGNOSIS OF VAGINAL INFECTIONS | LITMUS CONCEPTS, INC. (US) | 1998-02-19 | — | — | WO | disclosed |
| US-5660790-A | PH and amine test elements | LITMUS CONCEPTS, INC. (US) | 1997-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260085292-A1 | MINIMAL ESSENTIAL MEDIA FOR THE CULTURE OF HUMAN INDUCED PLURIPOTENT STEM CELLS | SLC7A11, GLUL, KCNN2 | TYMS 952/4885ESR2 3362/4885DHFR 1179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.