Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ACP1 | P24666 | 5/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22235999 | 0.88 | CDK5 (0.62) | CDK5CDK5R1HRH3FAAHAURKA | |
| SCHEMBL22258547 | 0.83 | LTA4H (0.39) | CDK5CDK5R1HRH3 | |
| SCHEMBL22258475 | 0.81 | NPC1 (0.49) | — | |
| SCHEMBL22258246 | 0.81 | NOS1 (0.40) | ACP1AURKARPS6KB1 | |
| SCHEMBL22258556 | 0.77 | TRPV1 (0.41) | AURKARPS6KB1AURKB | |
| SCHEMBL22258557 | 0.77 | STAT6 (0.41) | AURKARPS6KB1AURKB | |
| SCHEMBL22258549 | 0.76 | LTA4H (0.47) | — | |
| SCHEMBL22258481 | 0.74 | EGFR (0.55) | — | |
| SCHEMBL6734315 | 0.74 | HRH3 (0.54) | CDK5CDK5R1HRH3 | |
| SCHEMBL22258491 | 0.73 | RAB9A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150545-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF THE WNT/B-CATENIN SIGNALING PATHWAY | SAMUMED, LLC (US) | 2020-07-23 | — | — | WO | disclosed |