Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.39 |
| ▸ | RORB | Q92753 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | NOX1 | Q9Y5S8 | 4/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22271062 | 0.88 | LPAR1 (0.35) | RORCRORBLPAR1LPAR3KDR | |
| SCHEMBL22270563 | 0.85 | WNT3A (0.39) | RORCKDRPDE10AWNT3AHTT | |
| SCHEMBL22270885 | 0.82 | RORC (0.35) | RORCKDRPDE10ASMN1; SMN2 | |
| SCHEMBL22270668 | 0.81 | KDR (0.36) | RORCKDRPDE10AWNT3ASMN1; SMN2 | |
| SCHEMBL22270537 | 0.78 | MAPT (0.36) | KDRPDE10AWNT3ASMN1; SMN2 | |
| SCHEMBL22270880 | 0.77 | LMNA (0.37) | KDRPSMB5WNT3ASMN1; SMN2 | |
| SCHEMBL22270887 | 0.76 | KDM4E (0.40) | HTTSMN1; SMN2 | |
| SCHEMBL22270886 | 0.74 | L3MBTL1 (0.35) | PDE10A | |
| SCHEMBL22271073 | 0.74 | CCR1 (0.32) | — | |
| SCHEMBL19205607 | 0.72 | RORC (0.51) | RORCRORBLPAR1LPAR3WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |