Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22270563 | 0.83 | WNT3A (0.39) | KDRMAPTNPC1MEN1KMT2A | |
| SCHEMBL22270886 | 0.83 | L3MBTL1 (0.35) | POLBRAB9ANPSR1MAPTMEN1 | |
| SCHEMBL22270885 | 0.82 | RORC (0.35) | KDRPOLBRAB9ASMN1; SMN2MAPT | |
| SCHEMBL22270671 | 0.81 | RORC (0.39) | KDRSMN1; SMN2PDE10AWNT3ARORC | |
| SCHEMBL22270880 | 0.79 | LMNA (0.37) | KDRRAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL22271062 | 0.78 | LPAR1 (0.35) | KDRRORC | |
| SCHEMBL22270537 | 0.78 | MAPT (0.36) | KDRRAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL22271075 | 0.74 | RXRA (0.31) | — | |
| SCHEMBL22270601 | 0.72 | KDM4E (0.31) | HPGDALDH1A1GAARORC | |
| SCHEMBL22271066 | 0.71 | RORC (0.35) | MAPTRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |