Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 7/20 | 0.42 |
| ▸ | GHSR | Q92847 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28458976 | 0.81 | POLB (0.56) | POLBLTA4HGHSRKMT2A | |
| SCHEMBL21216250 | 0.79 | POLB (0.54) | POLBLTA4HGHSRKMT2A | |
| SCHEMBL22288105 | 0.77 | POLB (0.50) | POLBLTA4HGHSR | |
| SCHEMBL11419707 | 0.77 | GHSR (0.53) | POLBLTA4HGHSR | |
| SCHEMBL13220243 | 0.75 | POLB (0.59) | POLBLTA4HGHSRKMT2A | |
| SCHEMBL10685148 | 0.74 | POLB (0.57) | POLBLTA4HKMT2A | |
| SCHEMBL4293307 | 0.73 | G6PC1 (0.47) | — | |
| SCHEMBL13061032 | 0.72 | GHSR (0.48) | POLBLTA4HGHSR | |
| SCHEMBL13220245 | 0.71 | GHSR (0.53) | POLBLTA4HGHSR | |
| SCHEMBL1355696 | 0.71 | OPRM1 (0.59) | POLBLTA4HGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199681-A1 | OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS | EVONETIX LTD (GB) | 2024-06-20 | — | — | US | disclosed |
| US-11161869-B2 | Thermally-cleavable protecting and linker groups | EVONETIX LTD. (GB) | 2021-11-02 | — | — | US | disclosed |
| US-20210107934-A1 | THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS | SILICON VALLEY BANK | 2021-04-15 | — | — | US | disclosed |
| WO-2019145713-A9 | OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS | EVONETIX LTD (GB) | 2020-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199681-A1 | OLIGONUCLEOTIDE AND NUCLEIC ACID SYNTHESIS | POLN, POLI, ADAR | POLB 18/4885LTA4H 4009/4885GHSR 4466/4885 |
| US-20210107934-A1 | THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS | CTDSP1, RNGTT, SSU72 | POLB 24/4885LTA4H 2648/4885GHSR 4380/4885 |
| US-11161869-B2 | Thermally-cleavable protecting and linker groups | CTDSP1, RNGTT, SSU72 | POLB 24/4885LTA4H 2648/4885GHSR 4380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.