Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475144 | 0.85 | TSHR (0.43) | ALDH1A1SOAT1GAATSHRTDP1 | |
| SCHEMBL12120725 | 0.83 | ALDH1A1 (0.46) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL12315226 | 0.82 | ALDH1A1 (0.56) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL10087931 | 0.82 | ALDH1A1 (0.50) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL12987142 | 0.82 | ALDH1A1 (0.33) | ALDH1A1SOAT1LMNAHSD17B10TSHR | |
| SCHEMBL4736541 | 0.82 | HCAR2 (0.36) | ALDH1A1SOAT1LMNAHSD17B10TSHR | |
| SCHEMBL47990 | 0.80 | SOAT1 (0.42) | ALDH1A1SOAT1GAATSHRTDP1 | |
| SCHEMBL12315227 | 0.80 | ALDH1A1 (0.60) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL187396 | 0.80 | ALDH1A1 (0.60) | ALDH1A1SOAT1LMNAHSD17B10ALOX15 | |
| SCHEMBL16738135 | 0.80 | ALDH1A1 (0.39) | ALDH1A1SOAT1GAATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4234491-A | — | — | None | — | — | JP | disclosed |
| EP-2365957-B1 | METHOD FOR MAKING CARBONATES AND ESTERS | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2020-04-22 | — | — | EP | disclosed |
| US-20170267639-A1 | Process for Synthesizing Oxidized Lactam Compounds | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2017-09-21 | — | — | US | disclosed |
| US-9670200-B2 | Quaternary ammonium salt prodrugs | ALKERMES PHARMA IRELAND LIMITED (IE) | 2017-06-06 | — | — | US | disclosed |
| US-9650341-B2 | Process for synthesizing oxidized lactam compounds | ALKERMES PHARMA IRELAND LIMITED (IE) | 2017-05-16 | — | — | US | disclosed |
| US-20170097567-A1 | METHOD FOR PRODUCING POLYMER | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-04-06 | — | — | US | disclosed |
| US-9580417-B2 | Prodrugs of heteraromatic compounds | ALKERMES PHARMA IRELAND LIMITED (IE) | 2017-02-28 | — | — | US | disclosed |
| US-20170015659-A1 | Prodrugs of NH-Acidic Compounds | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2017-01-19 | — | — | US | disclosed |
| US-20160318869-A1 | Heterocyclic Compounds for the Treatment of Neurological and Psychological Disorders | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2016-11-03 | — | — | US | disclosed |
| US-20160229940-A1 | POLYMER, RESIST COMPOSITION, AND PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| WO-2010059318-A2 | METHOD FOR MAKING CARBONATES AND ESTERS | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-05-27 | — | — | WO | disclosed |
| US-20100123097-A1 | Method for Making Carbonates and Esters | SABIC INNOVATIVE PLASTICS IP BV (NL) | 2010-05-20 | — | — | US | disclosed |
| US-20080161394-A1 | Cosmetic composition comprising at least one volatile carbonic acid ester | L'OREAL S.A. (FR) | 2008-07-03 | — | — | US | disclosed |
| EP-0748364-A4 | UNLEADED MMT FUEL COMPOSITIONS | ORR WILLIAM C (US) | 1997-07-23 | — | — | EP | disclosed |
| EP-0748364-A1 | UNLEADED MMT FUEL COMPOSITIONS | ORR, William C. (US) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023836-A1 | UNLEADED MMT FUEL COMPOSITIONS | ORR WILLIAM C (US) | 1995-09-08 | — | — | WO | disclosed |
| US-5206408-A | Reacting symmetric dialkyl carbonate with alcohol in presence of cesium basic catalyst | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1993-04-27 | — | — | US | disclosed |
| JP-H04234491-A | ASYMMETRICAL DIALKYL CARBONATE FUEL ADDITIVE | ARCO CHEM TECHNOL INC | 1992-08-24 | — | — | JP | disclosed |
| EP-0474342-A1 | Unsymmetrical dialkyl carbonate fuel additives | ARCO Chemical Technology, L.P. (US) | 1992-03-11 | — | — | EP | disclosed |
| EP-0474342-A1 | Unsymmetrical dialkyl carbonate fuel additives | ARCO Chemical Technology, L.P. (US) | 1992-03-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318869-A1 | Heterocyclic Compounds for the Treatment of Neurological and Psychological Disorders | GABBR1, GABBR2, GABRE | ALDH1A1 599/4885SOAT1 2055/4885LMNA 1349/4885 |
| US-20170267639-A1 | Process for Synthesizing Oxidized Lactam Compounds | COASY, DHPS, OXA1L | ALDH1A1 113/4885SOAT1 602/4885LMNA 2901/4885 |
| US-20170015659-A1 | Prodrugs of NH-Acidic Compounds | SI, NAAA, NIT2 | ALDH1A1 1082/4885SOAT1 2112/4885LMNA 2642/4885 |
| US-20100123097-A1 | Method for Making Carbonates and Esters | ADH1C, ADH1A, ADH5 | ALDH1A1 471/4885SOAT1 414/4885LMNA 1364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.