SCHEMBL2229582

SCHEMBL2229582

OCC(O)CC1CCCN1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.46
CYP2D6 P10635 3/20 0.46
LMNA P02545 3/20 0.46
MEN1 O00255 2/20 0.46
TP53 P04637 2/20 0.46
KMT2A Q03164 2/20 0.46
GHSR Q92847 2/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP1A2 P05177 1/20 0.46
TSHR P16473 1/20 0.46
MLNR O43193 1/20 0.46
ABCB11 O95342 1/20 0.46
EGFR P00533 1/20 0.46
FYN P06241 1/20 0.46
CHRM2 P08172 1/20 0.46
CHRM4 P08173 1/20 0.46
HTR1A P08908 1/20 0.46
CHRM5 P08912 1/20 0.46
ADRA2A P08913 1/20 0.46
ADORA3 P0DMS8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2232026 0.94 CYP2D6 (0.53) FDPSCYP2D6LMNAMEN1TP53
SCHEMBL19143434 0.80
SCHEMBL6129772 0.80
SCHEMBL11705851 0.79 CYP2D6 (0.50) FDPSCYP2D6LMNAMEN1TP53
SCHEMBL2231729 0.78 ALDH1A1 (0.35) LMNAALDH1A1MAPT
SCHEMBL3586728 0.78 FDPS (0.44) FDPSCYP2D6LMNAMEN1TP53
SCHEMBL19476570 0.77 FDPS (0.41) FDPSCYP2D6LMNAMEN1TP53
SCHEMBL20028805 0.77 FDPS (0.41) FDPSCYP2D6LMNAMEN1TP53
SCHEMBL20028735 0.77 FDPS (0.41) FDPSCYP2D6LMNAMEN1TP53
SCHEMBL3955961 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8389772-B2 Aldehydes containing hydroxl groups SIKA TECHNOLOGY AG (CH) 2013-03-05 US claimed
US-20110195242-A1 ALDEHYDES CONTAINING HYDROXL GROUPS SIKA TECHNOLOGY AG (CH) 2011-08-11 US claimed
US-20100190014-A1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE SIKA TECHNOLOGY AG (CH) 2010-07-29 US claimed
EP-2200973-A1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE Sika Technology AG (CH) 2010-06-30 EP claimed
EP-2200970-A1 ALDEHYDES CONTAINING HYDROXYL GROUPS Sika Technology AG (CH) 2010-06-30 EP claimed
WO-2009027510-A1 ALDEHYDES CONTAINING HYDROXYL GROUPS SIKA TECHNOLOGY AG (CH) 2009-03-05 WO claimed
WO-2009027511-A1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE SIKA TECHNOLOGY AG (CH) 2009-03-05 WO claimed
EP-2030965-A1 Aldehydes containing hydroxyl groups Sika Technology AG (CH) 2009-03-04 EP claimed
EP-2030967-A1 Aldimines containing hydroxyl groups and compositions containing aldimine Sika Technology AG (CH) 2009-03-04 EP claimed
CN-101778814-B There is the aldehyde of hydroxyl SIKA技术股份公司 2016-08-03 CN disclosed
EP-2200970-B1 ALDEHYDES CONTAINING HYDROXYL GROUPS SIKA TECHNOLOGY AG (CH) 2016-01-06 EP disclosed
US-8455100-B2 Aldimines comprising hydroxyl groups, and compositions containing aldimine SIKA TECHNOLOGY AG (CH) 2013-06-04 US disclosed
US-8389772-B2 Aldehydes containing hydroxl groups SIKA TECHNOLOGY AG (CH) 2013-03-05 US disclosed
US-20110195242-A1 ALDEHYDES CONTAINING HYDROXL GROUPS SIKA TECHNOLOGY AG (CH) 2011-08-11 US disclosed
EP-2200973-A1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE Sika Technology AG (CH) 2010-06-30 EP disclosed
WO-2009027510-A1 ALDEHYDES CONTAINING HYDROXYL GROUPS SIKA TECHNOLOGY AG (CH) 2009-03-05 WO disclosed
WO-2009027511-A1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE SIKA TECHNOLOGY AG (CH) 2009-03-05 WO disclosed
EP-2030965-A1 Aldehydes containing hydroxyl groups Sika Technology AG (CH) 2009-03-04 EP disclosed
EP-2030967-A1 Aldimines containing hydroxyl groups and compositions containing aldimine Sika Technology AG (CH) 2009-03-04 EP disclosed
US-4391721-A Dispersant viscosity index improver comprising reaction product of a styrene-maleic anhydride copolymer, an aliphatic alcohol and a tertiary amino alcohol STANDARD OIL COMPANY (INDIANA) (US) 1983-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110195242-A1 ALDEHYDES CONTAINING HYDROXL GROUPS ALDH7A1, ALDH1A1, AOX1 FDPS 1646/4885CYP2D6 3243/4885LMNA 1740/4885
US-20100190014-A1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE ADH5, ADH1A, ADH1C FDPS 2141/4885CYP2D6 382/4885LMNA 1423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.