SCHEMBL2231729

SCHEMBL2231729

OCC(O)CC1CCCC(CC(O)CO)N1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2229582 0.78 FDPS (0.46) ALDH1A1LMNAMAPT
SCHEMBL2232026 0.77 CYP2D6 (0.53) ALDH1A1LMNAMAPT
SCHEMBL2945432 0.73
SCHEMBL4953332 0.69 DPP4 (0.34)
SCHEMBL2230154 0.69 DPP4 (0.34)
SCHEMBL13069245 0.69 DPP4 (0.34)
SCHEMBL4953344 0.69 DPP4 (0.34)
SCHEMBL6380793 0.69 TSHR (0.33) ALDH1A1LMNA
SCHEMBL15129648 0.67
SCHEMBL15129418 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2200970-B1 ALDEHYDES CONTAINING HYDROXYL GROUPS SIKA TECHNOLOGY AG (CH) 2016-01-06 EP disclosed
US-8455100-B2 Aldimines comprising hydroxyl groups, and compositions containing aldimine SIKA TECHNOLOGY AG (CH) 2013-06-04 US disclosed
US-8389772-B2 Aldehydes containing hydroxl groups SIKA TECHNOLOGY AG (CH) 2013-03-05 US disclosed
US-20110195242-A1 ALDEHYDES CONTAINING HYDROXL GROUPS SIKA TECHNOLOGY AG (CH) 2011-08-11 US disclosed
EP-2200973-B1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE SIKA TECHNOLOGY AG (CH) 2011-07-13 EP disclosed
US-20100190014-A1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE SIKA TECHNOLOGY AG (CH) 2010-07-29 US disclosed
EP-2200973-A1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE Sika Technology AG (CH) 2010-06-30 EP disclosed
EP-2200970-A1 ALDEHYDES CONTAINING HYDROXYL GROUPS Sika Technology AG (CH) 2010-06-30 EP disclosed
WO-2009027510-A1 ALDEHYDES CONTAINING HYDROXYL GROUPS SIKA TECHNOLOGY AG (CH) 2009-03-05 WO disclosed
WO-2009027511-A1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE SIKA TECHNOLOGY AG (CH) 2009-03-05 WO disclosed
EP-2030965-A1 Aldehydes containing hydroxyl groups Sika Technology AG (CH) 2009-03-04 EP disclosed
EP-2030967-A1 Aldimines containing hydroxyl groups and compositions containing aldimine Sika Technology AG (CH) 2009-03-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110195242-A1 ALDEHYDES CONTAINING HYDROXL GROUPS ALDH7A1, ALDH1A1, AOX1 ALDH1A1 2/4885LMNA 1740/4885MAPT 1835/4885
US-20100190014-A1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE ADH5, ADH1A, ADH1C ALDH1A1 6/4885LMNA 1423/4885MAPT 1624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.