Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MLNR | O43193 | 1/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229582 | 0.94 | FDPS (0.46) | CYP2D6MEN1LMNATP53KMT2A | |
| SCHEMBL11705851 | 0.85 | CYP2D6 (0.50) | CYP2D6MEN1LMNATP53KMT2A | |
| SCHEMBL29507344 | 0.79 | SLC6A2 (0.49) | CYP2D6MEN1LMNATP53KMT2A | |
| SCHEMBL15594567 | 0.78 | CYP2D6 (0.52) | CYP2D6MEN1LMNATP53KMT2A | |
| SCHEMBL11657826 | 0.78 | FDPS (0.47) | CYP2D6MEN1LMNATP53KMT2A | |
| SCHEMBL31318430 | 0.78 | CYP2D6 (0.55) | CYP2D6MEN1LMNATP53KMT2A | |
| SCHEMBL456091 | 0.78 | CYP2D6 (0.55) | CYP2D6MEN1LMNATP53KMT2A | |
| SCHEMBL2231729 | 0.77 | ALDH1A1 (0.35) | LMNAALDH1A1MAPT | |
| SCHEMBL9340447 | 0.77 | FDPS (0.46) | CYP2D6MEN1LMNATP53KMT2A | |
| SCHEMBL11702264 | 0.75 | FDPS (0.49) | CYP2D6MEN1LMNATP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101765583-B | Aldimines comprising hydroxyl groups, and compositions containing aldimine | SIKA TECHNOLOGY AG | 2014-06-04 | — | — | CN | claimed |
| US-8455100-B2 | Aldimines comprising hydroxyl groups, and compositions containing aldimine | SIKA TECHNOLOGY AG (CH) | 2013-06-04 | — | — | US | claimed |
| US-8389772-B2 | Aldehydes containing hydroxl groups | SIKA TECHNOLOGY AG (CH) | 2013-03-05 | — | — | US | claimed |
| US-20110195242-A1 | ALDEHYDES CONTAINING HYDROXL GROUPS | SIKA TECHNOLOGY AG (CH) | 2011-08-11 | — | — | US | claimed |
| US-20100190014-A1 | ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2010-07-29 | — | — | US | claimed |
| EP-2200973-A1 | ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE | Sika Technology AG (CH) | 2010-06-30 | — | — | EP | claimed |
| WO-2009027511-A1 | ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2009-03-05 | — | — | WO | claimed |
| EP-2030965-A1 | Aldehydes containing hydroxyl groups | Sika Technology AG (CH) | 2009-03-04 | — | — | EP | claimed |
| EP-2030967-A1 | Aldimines containing hydroxyl groups and compositions containing aldimine | Sika Technology AG (CH) | 2009-03-04 | — | — | EP | claimed |
| CN-101778814-B | There is the aldehyde of hydroxyl | SIKA技术股份公司 | 2016-08-03 | — | — | CN | disclosed |
| EP-2200970-B1 | ALDEHYDES CONTAINING HYDROXYL GROUPS | SIKA TECHNOLOGY AG (CH) | 2016-01-06 | — | — | EP | disclosed |
| CN-101765583-B | Aldimines comprising hydroxyl groups, and compositions containing aldimine | SIKA TECHNOLOGY AG | 2014-06-04 | — | — | CN | disclosed |
| US-8455100-B2 | Aldimines comprising hydroxyl groups, and compositions containing aldimine | SIKA TECHNOLOGY AG (CH) | 2013-06-04 | — | — | US | disclosed |
| US-8389772-B2 | Aldehydes containing hydroxl groups | SIKA TECHNOLOGY AG (CH) | 2013-03-05 | — | — | US | disclosed |
| EP-2200970-A1 | ALDEHYDES CONTAINING HYDROXYL GROUPS | Sika Technology AG (CH) | 2010-06-30 | — | — | EP | disclosed |
| EP-2200973-A1 | ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE | Sika Technology AG (CH) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009027510-A1 | ALDEHYDES CONTAINING HYDROXYL GROUPS | SIKA TECHNOLOGY AG (CH) | 2009-03-05 | — | — | WO | disclosed |
| WO-2009027511-A1 | ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2009-03-05 | — | — | WO | disclosed |
| EP-2030965-A1 | Aldehydes containing hydroxyl groups | Sika Technology AG (CH) | 2009-03-04 | — | — | EP | disclosed |
| EP-2030967-A1 | Aldimines containing hydroxyl groups and compositions containing aldimine | Sika Technology AG (CH) | 2009-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110195242-A1 | ALDEHYDES CONTAINING HYDROXL GROUPS | ALDH7A1, ALDH1A1, AOX1 | CYP2D6 3243/4885MEN1 4047/4885LMNA 1740/4885 |
| US-20100190014-A1 | ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE | ADH5, ADH1A, ADH1C | CYP2D6 382/4885MEN1 929/4885LMNA 1423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.