SCHEMBL2231395

SCHEMBL2231395

CC(O)CN(CC(C)O)CC(C)(C)C=O

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2246632 0.90 KDM4E (0.31) KDM4E
SCHEMBL4061686 0.84 CA12 (0.31) KDM4E
SCHEMBL2243775 0.82
SCHEMBL2250952 0.80
SCHEMBL9857947 0.75 KDM4E (0.34) KDM4E
SCHEMBL15512197 0.71 KDM4E (0.32) KDM4E
SCHEMBL15512625 0.71
SCHEMBL341251 0.70 PAX8 (0.35)
SCHEMBL25672259 0.70 KDM4E (0.34) KDM4E
SCHEMBL2230690 0.70 MAPT (0.32) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11149106-B2 Two-component polyurethane adhesive having substantially temperature-independent mechanical properties and high strength SIKA TECHNOLOGY AG (CH) 2021-10-19 US disclosed
EP-3283550-B1 CATALYST CONTAINING AMIDINE GROUPS SIKA TECH AG (CH) 2020-12-16 EP disclosed
EP-2895517-B1 TWO-COMPONENT POLYURETHANE COMPOSITION SIKA TECH AG (CH) 2020-12-16 EP disclosed
EP-3294803-B1 GUANIDINE GROUP CONTAINING CATALYST SIKA TECH AG (CH) 2020-12-09 EP disclosed
EP-3494155-B1 TWO COMPONENT POLYURETHANE ADHESIVE WITH SUBSTANTIALLY TEMPERATURE INDEPENDENT MECHANICAL PROPERTIES AND HIGH STRENGTH SIKA TECH AG (CH) 2020-09-09 EP disclosed
US-10414875-B2 Catalyst containing guanidine groups SIKA TECHNOLOGY AG (CH) 2019-09-17 US disclosed
US-10392480-B2 Catalyst containing amidine groups SIKA TECHNOLOGY AG (CH) 2019-08-27 US disclosed
US-20190169354-A1 TWO-COMPONENT POLYURETHANE ADHESIVE HAVING SUBSTANTIALLY TEMPERATURE-INDEPENDENT MECHANICAL PROPERTIES AND HIGH STRENGTH SIKA TECHNOLOGY AG (CH) 2019-06-06 US disclosed
EP-3372652-A1 WATER-SWELLABLE MOISTURE CURING ONE-COMPONENT POLYURETHANE SEALANT SIKA TECHNOLOGY AG (CH) 2018-09-12 EP disclosed
US-20180171082-A1 CATALYST CONTAINING AMIDINE GROUPS SIKA TECHNOLOGY AG (CH) 2018-06-21 US disclosed
US-8389772-B2 Aldehydes containing hydroxl groups SIKA TECHNOLOGY AG (CH) 2013-03-05 US disclosed
US-20110195242-A1 ALDEHYDES CONTAINING HYDROXL GROUPS SIKA TECHNOLOGY AG (CH) 2011-08-11 US disclosed
EP-2200973-B1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE SIKA TECHNOLOGY AG (CH) 2011-07-13 EP disclosed
US-20100190014-A1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE SIKA TECHNOLOGY AG (CH) 2010-07-29 US disclosed
EP-2200970-A1 ALDEHYDES CONTAINING HYDROXYL GROUPS Sika Technology AG (CH) 2010-06-30 EP disclosed
EP-2200973-A1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE Sika Technology AG (CH) 2010-06-30 EP disclosed
WO-2009027510-A1 ALDEHYDES CONTAINING HYDROXYL GROUPS SIKA TECHNOLOGY AG (CH) 2009-03-05 WO disclosed
WO-2009027511-A1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE SIKA TECHNOLOGY AG (CH) 2009-03-05 WO disclosed
EP-2030965-A1 Aldehydes containing hydroxyl groups Sika Technology AG (CH) 2009-03-04 EP disclosed
EP-2030967-A1 Aldimines containing hydroxyl groups and compositions containing aldimine Sika Technology AG (CH) 2009-03-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110195242-A1 ALDEHYDES CONTAINING HYDROXL GROUPS ALDH7A1, ALDH1A1, AOX1 KDM4E 559/4885
US-20100190014-A1 ALDIMINES COMPRISING HYDROXYL GROUPS, AND COMPOSITIONS CONTAINING ALDIMINE ADH5, ADH1A, ADH1C KDM4E 1105/4885
US-10414875-B2 Catalyst containing guanidine groups GMPS, GMNN, RNMT KDM4E 998/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.