Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.72 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.72 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MITF | O75030 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | TERT | O14746 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | YAP1 | P46937 | 3/20 | 0.54 |
| ▸ | TEAD4 | Q15561 | 3/20 | 0.54 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21392920 | 0.76 | RAB9A (0.69) | RAB9APOLBNCOA3NCOA1ALDH1A1 | |
| SCHEMBL21393103 | 0.70 | YAP1 (0.78) | RAB9APOLBNCOA3NCOA1ALDH1A1 | |
| SCHEMBL21392773 | 0.64 | YAP1 (1.00) | POLBTERTYAP1TEAD4MAPT | |
| SCHEMBL23052120 | 0.63 | ALDH1A1 (0.57) | RAB9APOLBNCOA3NCOA1ALDH1A1 | |
| SCHEMBL14541215 | 0.63 | ALDH1A1 (0.55) | RAB9APOLBNCOA3NCOA1ALDH1A1 | |
| SCHEMBL24767745 | 0.63 | P2RY6 (1.00) | POLBALDH1A1LMNAPKMSMN1; SMN2 | |
| SCHEMBL23052349 | 0.62 | POLB (0.66) | POLBALDH1A1LMNAPKMKDM4E | |
| SCHEMBL23268895 | 0.61 | ALDH1A1 (0.64) | ALDH1A1 | |
| SCHEMBL23052458 | 0.61 | ALDH1A1 (0.80) | RAB9AALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL11333537 | 0.61 | TDP1 (0.57) | RAB9APOLBNCOA3NCOA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200278355-A1 | CONJUGATED PROTEINS AND USES THEREOF | SCRIPPS RESEARCH INST (US) | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200278355-A1 | CONJUGATED PROTEINS AND USES THEREOF | KEAP1, GSTK1, GSTM2 | RAB9A 2876/4885POLB 3140/4885NCOA3 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.