Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.69 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | MITF | O75030 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.64 |
| ▸ | YAP1 | P46937 | 3/20 | 0.57 |
| ▸ | TEAD4 | Q15561 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.51 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21393103 | 0.79 | YAP1 (0.78) | RAB9APOLBNCOA3NCOA1ALDH1A1 | |
| SCHEMBL22387595 | 0.76 | RAB9A (0.72) | RAB9APOLBNCOA3NCOA1ALDH1A1 | |
| SCHEMBL23052349 | 0.73 | POLB (0.66) | POLBALDH1A1LMNAPKMXDH | |
| SCHEMBL21392773 | 0.70 | YAP1 (1.00) | POLBYAP1TEAD4 | |
| SCHEMBL16740601 | 0.70 | PTGS2 (0.61) | POLBALDH1A1 | |
| SCHEMBL14540778 | 0.69 | ALDH1A1 (0.56) | POLBALDH1A1XDH | |
| SCHEMBL23052458 | 0.68 | ALDH1A1 (0.80) | RAB9AALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL23268895 | 0.67 | ALDH1A1 (0.64) | ALDH1A1XDH | |
| SCHEMBL14540723 | 0.67 | ALDH1A1 (0.57) | POLBALDH1A1LMNAHTTXDH | |
| SCHEMBL23052089 | 0.67 | KMT2A (0.71) | ALDH1A1LMNAXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11666661-B2 | Methods and compounds for targeted autophagy | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-06 | — | — | US | disclosed |
| US-11666661-B2 | Methods and compounds for targeted autophagy | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-06 | — | — | US | disclosed |
| US-20210369731-A1 | COVALENT TARGETING OF E3 LIGASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-12-02 | — | — | US | disclosed |
| US-20190290778-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | FRONTIER MEDICINES CORPORATION | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190290778-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | ATG7, BECN1, SQSTM1 | RAB9A 223/4885POLB 2880/4885NCOA3 893/4885 |
| US-20210369731-A1 | COVALENT TARGETING OF E3 LIGASES | RNF114, RNF4, RNF168 | RAB9A 2224/4885POLB 3939/4885NCOA3 686/4885 |
| US-11666661-B2 | Methods and compounds for targeted autophagy | ATG7, BECN1, SQSTM1 | RAB9A 223/4885POLB 2880/4885NCOA3 893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.