Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL734326 | 0.98 | DNM1 (0.39) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL110290 | 0.94 | LMNA (0.32) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL31719619 | 0.89 | DNM1 (0.43) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL8729872 | 0.88 | NFKB1 (0.30) | — | |
| SCHEMBL28411728 | 0.88 | NFKB1 (0.30) | — | |
| SCHEMBL6896664 | 0.88 | NFKB1 (0.30) | — | |
| SCHEMBL691752 | 0.86 | LMNA (0.42) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL2356022 | 0.86 | DNM1 (0.33) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL28858270 | 0.85 | LMNA (0.31) | LMNA | |
| SCHEMBL28554977 | 0.85 | LMNA (0.44) | DNM1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718755-B1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL INC (US) | 2024-05-29 | — | — | EP | disclosed |
| EP-3563185-B1 | POLARIZING ARTICLE AND METHOD OF FORMING A POLARIZING ARTICLE | TRANSITIONS OPTICAL LTD (IE) | 2024-01-31 | — | — | EP | disclosed |
| EP-2718754-B1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL INC (US) | 2024-01-24 | — | — | EP | disclosed |
| EP-2895896-B1 | A PHOTOCHROMIC ARTICLE HAVING AT LEAST PARTIALLY CROSSED POLARIZED PHOTOCHROMIC-DICHROIC AND FIXED-POLARIZED LAYERS | TRANSITIONS OPTICAL INC (US) | 2022-11-02 | — | — | EP | disclosed |
| US-10884288-B2 | Polarizing article and method of forming a polarizing article | TRANSITIONS OPTICAL, LTD. (IE) | 2021-01-05 | — | — | US | disclosed |
| US-20200103571-A1 | Polarizing Article and Method of Forming a Polarizing Article | TRANSITIONS OPTICAL, LTD. (IE) | 2020-04-02 | — | — | US | disclosed |
| EP-2895897-B1 | A PHOTOCHROMIC ARTICLE HAVING TWO AT LEAST PARTIALLY CROSSED PHOTOCHROMIC-DICHROIC LAYERS | TRANSITIONS OPTICAL INC (US) | 2020-03-25 | — | — | EP | disclosed |
| US-10590220-B2 | Photoalignment materials having improved adhesion | TRANSITIONS OPTICAL, INC. (US) | 2020-03-17 | — | — | US | disclosed |
| US-20170037173-A1 | Photoalignment Materials Having Improved Adhesion | TRANSITIONS OPTICAL, INC. | 2017-02-09 | — | — | US | disclosed |
| US-9475901-B2 | Photoalignment materials having improved adhesion | TRANSITIONS OPTICAL, INC. (US) | 2016-10-25 | — | — | US | disclosed |
| WO-2012082299-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | WO | disclosed |
| US-20120120473-A1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 2012-05-17 | — | — | US | disclosed |
| US-20120027960-A1 | MESOGENIC STABILIZERS | TRANSITIONS OPTICAL, INC. (US) | 2012-02-02 | — | — | US | disclosed |
| US-20120002141-A1 | MESOGENIC STABILIZERS | TRANSITIONS OPTICAL, INC. (US) | 2012-01-05 | — | — | US | disclosed |
| US-20120003401-A1 | MESOGENIC STABILIZERS | TRANSITIONS OPTICAL, INC. (US) | 2012-01-05 | — | — | US | disclosed |
| US-20110279883-A1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 2011-11-17 | — | — | US | disclosed |
| US-20110143141-A1 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2011-06-16 | — | — | US | disclosed |
| WO-2011071794-A1 | PHOTOALIGNMENT MATERIALS HAVING IMPROVED ADHESION | TRANSITIONS OPTICAL, INC. (US) | 2011-06-16 | — | — | WO | disclosed |
| US-20110135850-A1 | PHOTOALIGNMENT MATERIALS HAVING IMPROVED ADHESION | TRANSITIONS OPTICAL, INC. (US) | 2011-06-09 | — | — | US | disclosed |
| US-20110129678-A1 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2011-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110143141-A1 | Photochromic compounds and compositions | CCNA1, CRY1, CCNT1 | DNM1 3515/4885MEN1 437/4885KMT2A 563/4885 |
| US-20120027960-A1 | MESOGENIC STABILIZERS | C1S, PYM1, H1-0 | DNM1 1971/4885MEN1 90/4885KMT2A 259/4885 |
| US-20120003401-A1 | MESOGENIC STABILIZERS | PYM1, BMI1, C1S | DNM1 1082/4885MEN1 17/4885KMT2A 375/4885 |
| US-20120002141-A1 | MESOGENIC STABILIZERS | BMI1, METTL14, PYM1 | DNM1 1040/4885MEN1 8/4885KMT2A 293/4885 |
| US-20110129678-A1 | Photochromic compounds and compositions | CRY2, CRY1, PPOX | DNM1 4219/4885MEN1 3110/4885KMT2A 1960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.