Sugi Predict

Sugi Predict / Compounds / Silver

Silver

Silver

SCHEMBL2239077

O=C([O-])CCCO[N+](=O)[O-].[Ag+]

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

folP

The experimentally established mechanism targets of Silver. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 5/20 0.38
▸ CA12 O43570 4/20 0.37
▸ CA2 P00918 4/20 0.37
▸ CA4 P22748 4/20 0.37
▸ CA9 Q16790 4/20 0.37
▸ ESR2 Q92731 2/20 0.37
▸ BBOX1 O75936 1/20 0.35
▸ PTGS2 P35354 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Silver SCHEMBL2236901 0.92 CA1 (0.39) CA1CA12CA2CA4CA9
SCHEMBL457635 0.80 LMNA (0.44) CA1CA12CA2CA4CA9
SCHEMBL2014045 0.80 CA12 (0.41) CA1CA12CA2CA4CA9
SCHEMBL5039623 0.78 ALDH1A1 (0.39) CA1CA12CA2CA4CA9
Methane SCHEMBL2013629 0.78 LMNA (0.43) CA1CA12CA2CA4CA9
SCHEMBL13979249 0.78 PTGS2 (0.41) CA1CA12CA2CA4CA9
Ethane SCHEMBL2012141 0.77 ESR2 (0.42) ESR2PTGS2ALDH1A1
SCHEMBL1220763 0.75 CA12 (0.48) CA1CA12CA2CA4CA9
SCHEMBL4731008 0.75 CA12 (0.48) CA1CA12CA2CA4CA9
SCHEMBL2013628 0.75 TSHR (0.54) ESR2PTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011101245-A1 NITRIC OXIDE RELEASING COMPOUNDS FOR THE TREATMENT OF NEUROPATHIC PAIN NICOX S.A. (FR) 2011-08-25 — — WO disclosed
WO-2011092065-A1 NITRIC OXIDE RELEASING COMPOUNDS FOR THE TREATMENT OF NEUROPHATIC PAIN NICOX S.A. (FR) 2011-08-04 — — WO disclosed