Ethane

Ethane

SCHEMBL2012141

CC.O=C(O)CCCO[N+](=O)[O-]

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 3/20 0.41
MEN1 O00255 1/20 0.41
BLM P54132 1/20 0.41
HBB P68871 1/20 0.41
KMT2A Q03164 1/20 0.41
HIF1A Q16665 1/20 0.41
SLC22A6 Q4U2R8 1/20 0.40
TSHR P16473 3/20 0.39
NFKB1 P19838 1/20 0.39
PMP22 Q01453 1/20 0.39
AKR1B1 P15121 1/20 0.38
PTGS2 P35354 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL457635 0.96 LMNA (0.44) ESR2ALDH1A1LMNAMEN1BLM
Ethane SCHEMBL2016586 0.94 ALDH1A1 (0.50) ESR2ALDH1A1LMNAMEN1BLM
Methane SCHEMBL2013629 0.94 LMNA (0.43) ESR2ALDH1A1LMNAMEN1BLM
Ethane SCHEMBL2011976 0.92 ALDH1A1 (0.53) ESR2ALDH1A1LMNAMEN1KMT2A
Ethane SCHEMBL2014497 0.92 ALDH1A1 (0.53) ESR2ALDH1A1LMNAMEN1KMT2A
Ethane SCHEMBL2012552 0.92 ALDH1A1 (0.53) ESR2ALDH1A1LMNAMEN1KMT2A
Ethane SCHEMBL2014852 0.92 ALDH1A1 (0.53) ESR2ALDH1A1LMNAMEN1KMT2A
Ethane SCHEMBL2015424 0.92 ALDH1A1 (0.53) ESR2ALDH1A1LMNAMEN1KMT2A
Ethane SCHEMBL14151972 0.92 ALDH1A1 (0.53) ESR2ALDH1A1LMNAMEN1KMT2A
SCHEMBL399991 0.89 ALDH1A1 (0.48) ESR2ALDH1A1LMNAMEN1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10154981-B2 Use of a feed composition for reducing methane emission in ruminants, and/or to improve ruminant performance DSM IP ASSETS B.V. (NL) 2018-12-18 US claimed
EP-3041365-B1 USE OF A FEED COMPOSITION FOR REDUCING METHANE EMISSION IN RU-MINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS BV (NL) 2018-04-04 EP claimed
US-20160183564-A1 USE OF A FEED COMPOSITION FOR REDUCING METHANE EMISSION IN RUMINANTS, AND OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS B.V. (NL) 2016-06-30 US claimed
CN-103561586-B Fodder compound is for reducing the discharge of methane of ruminant and/or improving the purposes that ruminant shows DSM IP ASSETS B.V. (NL) 2016-05-04 CN claimed
CN-105472995-A Use of feed composition for reducing methane emission in ru-minants, and/or to improve ruminant performance DSM IP ASSETS BV 2016-04-06 CN claimed
US-20240189408-A1 COMPOSITIONS AND METHODS FOR REDUCING METHANE EMISSIONS IN RUMINANT POPULATIONS Arkea Bio Corp. 2024-06-13 US disclosed
WO-2024015366-A1 COMPOSITIONS AND METHODS FOR REDUCING METHANE EMISSIONS IN RUMINANT POPULATIONS Arkea Bio Corp. (US) 2024-01-18 WO disclosed
US-20240009291-A1 COMPOSITIONS AND METHODS FOR REDUCING METHANE EMISSIONS IN RUMINANT POPULATIONS Arkea Bio Corp. 2024-01-11 US disclosed
US-11191288-B2 Use of a feed composition for reducing methane emission in ruminants, and/or to improve ruminant performance DSM IP ASSETS B.V. (NL) 2021-12-07 US disclosed
US-20200229465-A1 USE OF A FEED COMPOSITION FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS B.V. (NL) 2020-07-23 US disclosed
US-10154981-B2 Use of a feed composition for reducing methane emission in ruminants, and/or to improve ruminant performance DSM IP ASSETS B.V. (NL) 2018-12-18 US disclosed
EP-3041365-B1 USE OF A FEED COMPOSITION FOR REDUCING METHANE EMISSION IN RU-MINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS BV (NL) 2018-04-04 EP disclosed
EP-2713766-B1 USE OF A FEED COMPOSITION FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS BV (NL) 2015-06-24 EP disclosed
US-8784871-B2 Nitrooxy alkanoic acids and derivatives thereof in feed for reducing methane emission in ruminants, and/or to improve ruminant performance DSM IP ASSETS B.V. (NL) 2014-07-22 US disclosed
US-20140134282-A1 NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS B.V. (NL) 2014-05-15 US disclosed
US-20140088161-A1 USE OF A FEED COMPOSITION FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS B.V. (NL) 2014-03-27 US disclosed
EP-2509435-B1 NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS BV (NL) 2014-02-26 EP disclosed
US-20120315339-A1 NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS B.V. (NL) 2012-12-13 US disclosed
EP-2509435-A1 NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP Assets B.V. (NL) 2012-10-17 EP disclosed
WO-2011070133-A1 NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE DSM IP ASSETS B.V. (NL) 2011-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140134282-A1 NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE PIGS, TECR, CYP4X1 ESR2 2668/4885ALDH1A1 2126/4885LMNA 901/4885
US-20120315339-A1 NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE PIGS, TECR, CYP4X1 ESR2 2668/4885ALDH1A1 2126/4885LMNA 901/4885
US-20140088161-A1 USE OF A FEED COMPOSITION FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE OAT, MRM1, ETFA ESR2 835/4885ALDH1A1 2035/4885LMNA 4078/4885
US-20240009291-A1 COMPOSITIONS AND METHODS FOR REDUCING METHANE EMISSIONS IN RUMINANT POPULATIONS MT-CO2, CYB5R3, COX5A ESR2 1499/4885ALDH1A1 1529/4885LMNA 1999/4885
US-10154981-B2 Use of a feed composition for reducing methane emission in ruminants, and/or to improve ruminant performance OAT, MRM1, ETFA ESR2 835/4885ALDH1A1 2035/4885LMNA 4078/4885
US-20240189408-A1 COMPOSITIONS AND METHODS FOR REDUCING METHANE EMISSIONS IN RUMINANT POPULATIONS MT-CO2, CYB5R3, COX5A ESR2 1499/4885ALDH1A1 1529/4885LMNA 1999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.