Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL2013629 | 0.98 | LMNA (0.43) | LMNABLMKMT2AMEN1HBB | |
| Ethane SCHEMBL2012141 | 0.96 | ESR2 (0.42) | LMNABLMKMT2AMEN1HBB | |
| SCHEMBL399991 | 0.93 | ALDH1A1 (0.48) | LMNABLMKMT2AMEN1HBB | |
| SCHEMBL2011462 | 0.91 | ALDH1A1 (0.52) | LMNABLMKMT2AMEN1HBB | |
| Methane SCHEMBL2010264 | 0.91 | ALDH1A1 (0.47) | LMNABLMKMT2AMEN1HBB | |
| SCHEMBL398562 | 0.91 | ALDH1A1 (0.52) | LMNABLMKMT2AMEN1HBB | |
| SCHEMBL14894607 | 0.91 | ALDH1A1 (0.52) | LMNABLMKMT2AMEN1HBB | |
| SCHEMBL2010277 | 0.91 | ALDH1A1 (0.52) | LMNABLMKMT2AMEN1HBB | |
| SCHEMBL2011072 | 0.91 | ALDH1A1 (0.52) | LMNABLMKMT2AMEN1HBB | |
| SCHEMBL2011728 | 0.91 | ALDH1A1 (0.52) | LMNABLMKMT2AMEN1HBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3618819-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | Exciva GmbH (DE) | 2020-03-11 | — | — | EP | claimed |
| US-20200069674-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | Exciva GmbH (DE) | 2020-03-05 | — | — | US | claimed |
| CN-110831584-A | Targeted drug rescue with novel compositions, combinations and methods thereof | 埃克塞瓦有限责任公司 | 2020-02-21 | — | — | CN | claimed |
| EP-3220905-B1 | COMBINATIONS OF PROSTAGLANDINS AND NITRIC OXIDE DONORS | NICOX SA (FR) | 2019-10-09 | — | — | EP | claimed |
| WO-2018204713-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | EXCIVA UG (HAFTUNGSBESCHRÄNKT) (DE) | 2018-11-08 | — | — | WO | claimed |
| EP-3041365-B1 | USE OF A FEED COMPOSITION FOR REDUCING METHANE EMISSION IN RU-MINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE | DSM IP ASSETS BV (NL) | 2018-04-04 | — | — | EP | claimed |
| EP-2509435-B1 | NITROOXY ALKANOIC ACIDS AND DERIVATIVES THEREOF IN FEED FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE | DSM IP ASSETS BV (NL) | 2014-02-26 | — | — | EP | claimed |
| EP-2229161-A2 | COMPOSITION COMPRISING A NITROOXYDERIVATIVE OF ACETAMINOPHEN AND A ANTICONVULSANT DRUG FOR THE TREATMENT OF NEUROPATHIC PAIN | Nicox S.A. (FR) | 2010-09-22 | — | — | EP | claimed |
| WO-2009087005-A2 | COMPOSITION COMPRISING A NITROOXYDERIVATIVE OF ACETAMINOPHEN AND A ANTICONVULSANT DRUG FOR THE TREATMENT OF NEUROPATHIC PAIN | NICOX S.A. (FR) | 2009-07-16 | — | — | WO | claimed |
| US-7166605-B2 | Probucol nitro-derivatives | NICOX, S.A. (FR) | 2007-01-23 | — | — | US | claimed |
| US-20060167003-A1 | Probucol derivatives | NICOX S.A. (FR) | 2006-07-27 | — | — | US | claimed |
| EP-1521740-A2 | PROBUCOL DERIVATIVES | Nicox S.A. (FR) | 2005-04-13 | — | — | EP | claimed |
| WO-2003080568-A2 | PROBUCOL DERIVATIVES | NICOX S.A. (FR) | 2003-10-02 | — | — | WO | claimed |
| US-20260028324-A1 | NITRIC OXIDE RELEASING PRODRUGS OF MDA AND MDMA | EMPATHBIO INC (US) | 2026-01-29 | — | — | US | disclosed |
| US-12454516-B2 | Nitric oxide releasing prodrugs of MDA and MDMA | EMPATHBIO, INC. (US) | 2025-10-28 | — | — | US | disclosed |
| CN-115959996-B | NO donor compound, pharmaceutical composition and application thereof | 上海众强药业有限公司 | 2025-02-18 | — | — | CN | disclosed |
| EP-0541634-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | CEDONA PHARMACEUTICALS B.V. (NL) | 1993-05-19 | — | — | EP | disclosed |
| WO-1992002503-A1 | NOVEL 1,4-DIHYDROPYRIDINE DERIVATIVES | CEDONA PHARMACEUTICALS BV (NL) | 1992-02-20 | — | — | WO | disclosed |
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |
| US-4801596-A | Nitroxy amino propanols for treating heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1989-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200069674-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | HTR2A, HTR2C, CYP3A43 | LMNA 1421/4885BLM 1267/4885KMT2A 1669/4885 |
| US-20060167003-A1 | Probucol derivatives | PNLIP, APOB, LIPC | LMNA 210/4885BLM 865/4885KMT2A 4806/4885 |
| US-20260028324-A1 | NITRIC OXIDE RELEASING PRODRUGS OF MDA AND MDMA | DBH, SLC6A3, SLC6A2 | LMNA 1614/4885BLM 2351/4885KMT2A 3918/4885 |
| US-12454516-B2 | Nitric oxide releasing prodrugs of MDA and MDMA | NOS1, NOS3, NOS2 | LMNA 4013/4885BLM 2212/4885KMT2A 2419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.