SCHEMBL2239140

SCHEMBL2239140

CN1CN(C)C(=O)N(O)C1=O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.32
CRBN Q96SW2 1/20 0.31
BRD4 O60885 1/20 0.31
BRD2 P25440 1/20 0.31
ADRA2C P18825 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12252009 0.81
SCHEMBL11607389 0.75 KMT2A (0.35) KMT2ACRBNBRD4BRD2ADRA2C
Hydrochloric Acid SCHEMBL11349959 0.73 KMT2A (0.33) KMT2ACRBNBRD4BRD2ADRA2C
Bromide SCHEMBL11607704 0.73 KMT2A (0.33) KMT2ACRBNBRD4BRD2ADRA2C
SCHEMBL2238464 0.72
SCHEMBL15247796 0.69
SCHEMBL9122897 0.69 KMT2A (0.35) KMT2ACRBNBRD4BRD2ADRA2C
SCHEMBL13710828 0.69
SCHEMBL2235528 0.69 BRD4 (0.41) BRD4BRD2
SCHEMBL228923 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2248792-B1 PROCESS FOR PRODUCTION OF OXYGEN-CONTAINING ORGANIC COMPOUND DAICEL CHEM (JP) 2013-11-27 EP disclosed
US-8410308-B2 Process for production of oxygen-containing organic compound DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2013-04-02 US disclosed
EP-2096097-B1 METHOD FOR PRODUCING OXIDATION PRODUCT OF CYCLOALKANE DAICEL CHEM (JP) 2012-08-22 EP disclosed
US-7994330-B2 Oxidizing p-xylene to terephthalic acid using a catalyst having a dicarboximide skeleton; hydrothermally treating the product with hot water, decomposing and removing catalyst impurities DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2011-08-09 US disclosed
US-20100331569-A1 PROCESS FOR PRODUCTION OF OXYGEN-CONTAINING ORGANIC COMPOUND DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2010-12-30 US disclosed
US-7834217-B2 Method for producing oxidation product of cycloalkane DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2010-11-16 US disclosed
EP-2248792-A1 PROCESS FOR PRODUCTION OF OXYGEN-CONTAINING ORGANIC COMPOUND Daicel Chemical Industries, Ltd. (JP) 2010-11-10 EP disclosed
US-20100081848-A1 METHOD FOR PRODUCING OXIDATION PRODUCT OF CYCLOALKANE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2010-04-01 US disclosed
US-20100029956-A1 METHOD FOR PRODUCING ESTER OR LACTONE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2010-02-04 US disclosed
EP-2123646-A1 METHOD FOR PRODUCING ESTER OR LACTONE Daicel Chemical Industries, Ltd. (JP) 2009-11-25 EP disclosed
US-7034184-B2 Process for producing azine compounds and oxime compounds DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-04-25 US disclosed
US-20060030716-A1 Catalyst comprising cyclic acylurea compound and process for producing organic compounds using the catalyst ISHII YASUTAKA 2006-02-09 US disclosed
US-20050020439-A1 Catalyst comprising cyclic acylurea compounds and processes for production organic compounds with the same DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2005-01-27 US disclosed
EP-1342714-B1 Process for producing azine compounds and oxime compounds DAICEL CHEM (JP) 2005-01-26 EP disclosed
EP-1459804-A1 CATALYSTS COMPRISING CYCLIC ACYLUREA COMPOUNDS AND PROCESSES FOR PRODUCTION OF ORGANIC COMPOUNDS WITH THE SAME Daicel Chemical Industries, Ltd. (JP) 2004-09-22 EP disclosed
US-6768023-B2 REACTING AN ESTER OR SALT OF NITROUS ACID WITH A COMPOUND THAT GENERATES A FREE RADICAL IN THE PRESENCE OF A NITROGEN CONTAINING CYCLIC COMPOUND CONTAINING AN N-OXY OR -HYDROXY IMIDE GROUP; FORMING OXIMES, NITRO COMPOUNDS, AND KETONES DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-07-27 US disclosed
US-20030204084-A1 Process for producing azine compounds and oxime compounds DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-10-30 US disclosed
US-20030171618-A1 Process for producing organic compounds using nitrites DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-09-11 US disclosed
EP-1342715-A2 Process for producing oximes using nitirites Daicel Chemical Industries, Ltd. (JP) 2003-09-10 EP disclosed
EP-1342714-A1 Process for producing azine compounds and oxime compounds Daicel Chemical Industries, Ltd. (JP) 2003-09-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030204084-A1 Process for producing azine compounds and oxime compounds CBR1, DAO, ALKBH2 KMT2A 1581/4885CRBN 429/4885BRD4 3393/4885
US-20030171618-A1 Process for producing organic compounds using nitrites NOS1, NOS2, NOS3 KMT2A 3719/4885CRBN 355/4885BRD4 4162/4885
US-20100029956-A1 METHOD FOR PRODUCING ESTER OR LACTONE RIOX2, CBR1, AKR7A2 KMT2A 3324/4885CRBN 1233/4885BRD4 2225/4885
US-20100081848-A1 METHOD FOR PRODUCING OXIDATION PRODUCT OF CYCLOALKANE CBR3, CBR1, CYCS KMT2A 4012/4885CRBN 2837/4885BRD4 4751/4885
US-20100331569-A1 PROCESS FOR PRODUCTION OF OXYGEN-CONTAINING ORGANIC COMPOUND HAO2, SCO2, CYC1 KMT2A 2843/4885CRBN 1630/4885BRD4 3580/4885
US-20060030716-A1 Catalyst comprising cyclic acylurea compound and process for producing organic compounds using the catalyst MOGAT2, HAT1, ACOX1 KMT2A 1306/4885CRBN 2979/4885BRD4 3479/4885
US-20050020439-A1 Catalyst comprising cyclic acylurea compounds and processes for production organic compounds with the same MOGAT2, ACSS2, ACOX1 KMT2A 1623/4885CRBN 2910/4885BRD4 3616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.