Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | IGF1R | P08069 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | BRAF | P15056 | 2/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | AXL | P30530 | 2/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 2/20 | 0.35 |
| ▸ | FNTB | P49356 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27201661 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4EP2RX7 | |
| SCHEMBL21494223 | 0.70 | TSHR (0.47) | ALDH1A1KDM4E | |
| SCHEMBL29007748 | 0.67 | HSD11B1 (0.43) | ALDH1A1SMN1; SMN2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL16333106 | 0.66 | OPRM1 (0.40) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL27201684 | 0.64 | HDAC4 (0.47) | CDK2ALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL258223 | 0.63 | ALDH1A1 (0.55) | ALDH1A1KDM4ESMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL158842 | 0.63 | POLB (0.49) | ALDH1A1KDM4ESMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL5765163 | 0.63 | GABRA1 (0.56) | — | |
| SCHEMBL17397770 | 0.63 | MEN1 (0.40) | — | |
| SCHEMBL6218871 | 0.63 | RBP4 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212973-A1 | CARBAMATE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-09-01 | — | — | US | disclosed |
| EP-2351749-A1 | CARBAMATE COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2011-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212973-A1 | CARBAMATE COMPOUND OR SALT THEREOF | FAAH, FAAH2, TRPV1 | CDK1 2752/4885IGF1R 4844/4885FGFR1 1579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.