SCHEMBL2241867

SCHEMBL2241867

N=C(N)NCCC[C@H](NC(=O)CN)C(=O)N[C@@H](CCCCN)C(=O)[O-].N=C(N)NCCC[C@H](NC(=O)CN)C(=O)N[C@@H](CCCCN)C(=O)[O-].[Cu+2]

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NMT1 P30419 5/20 0.42
▸ NMT2 O60551 4/20 0.42
▸ SLC15A2 Q16348 1/20 0.42
▸ NPY4R P50391 9/20 0.41
▸ NPY5R Q15761 9/20 0.41
▸ NPY1R P25929 8/20 0.41
▸ NPY2R P49146 6/20 0.41
▸ SIRT6 Q8N6T7 1/20 0.40
▸ SIRT1 Q96EB6 1/20 0.40
▸ TLR2 O60603 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4589289 0.98 NMT1 (0.42) NMT1NMT2SLC15A2NPY4RNPY5R
SCHEMBL2815692 0.90 NPY4R (0.36) SLC15A2NPY4RNPY5RNPY1RNPY2R
SCHEMBL29516817 0.89 TLR2 (0.48) NMT1NMT2NPY4RNPY5RNPY1R
SCHEMBL2814907 0.89 NMT2 (0.42) NMT1NMT2NPY4RNPY5RNPY1R
SCHEMBL31106970 0.88 SLC15A2 (0.51) NMT1NMT2SLC15A2NPY4RNPY5R
SCHEMBL30372694 0.88 SLC15A2 (0.51) NMT1NMT2SLC15A2NPY4RNPY5R
SCHEMBL30713830 0.88 SLC15A2 (0.51) NMT1NMT2SLC15A2NPY4RNPY5R
SCHEMBL30373028 0.88 SLC15A2 (0.51) NMT1NMT2SLC15A2NPY4RNPY5R
SCHEMBL31717990 0.88 SLC15A2 (0.51) NMT1NMT2SLC15A2NPY4RNPY5R
SCHEMBL29461533 0.88 SLC15A2 (0.51) NMT1NMT2SLC15A2NPY4RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110206790-A1 Antimicrobial Foamable Soaps OHSO CLEAN, INC 2011-08-25 — — US disclosed
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS PROCYTE CORPORATION (US) 2010-09-30 — — US disclosed
EP-1613302-B1 PRESERVED AND STABLE COMPOSITIONS CONTAINING PEPTIDE COPPER COMPLEXES AND METHODS RELATED THERETO PROCYTE CORP (US) 2009-12-23 — — EP disclosed
US-7179789-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2007-02-20 — — US disclosed
US-7128923-B2 Preserved and stable compositions containing peptide copper complexes and method related thereto PROCYTE CORPORATION (US) 2006-10-31 — — US disclosed
US-20060052287-A1 Polyethylene glycol - peptide copper complexes and compositions and methods related thereto PROCYTE CORPORATION (US) 2006-03-09 — — US disclosed
US-20050260275-A1 Encapsulated peptide copper complexes and compositions and methods related thereto PROCYTE CORPORATION (US) 2005-11-24 — — US disclosed
US-20050209130-A1 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-09-22 — — US disclosed
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PROCYTE CORPORATION (US) 2005-09-08 — — US disclosed
US-6927205-B2 Compositions and methods for treatment of psoriasis PROCYTE CORPORATION (US) 2005-08-09 — — US disclosed
US-6927206-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-08-09 — — US disclosed
EP-0765152-B1 STIMULATION OF HAIR GROWTH BY PEPTIDE-COPPER COMPLEXES PROCYTE CORP (US) 2001-11-07 — — EP disclosed
WO-1994018230-A1 INHIBITION OF HIV REPLICATION BY PEPTIDE-COPPER COMPLEXES PROCYTE CORPORATION (US) 1994-08-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050209130-A1 Compositions and methods for treatment of rosacea CUTA, AOC1, RCN1 NMT1 4107/4885NMT2 3869/4885SLC15A2 2091/4885
US-20060052287-A1 Polyethylene glycol - peptide copper complexes and compositions and methods related thereto NGLY1, CUTA, TFRC NMT1 1434/4885NMT2 1991/4885SLC15A2 1553/4885
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS CUTA, TYR, EYA3 NMT1 3403/4885NMT2 2644/4885SLC15A2 2514/4885
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PTH1R, TSLP, CYP27B1 NMT1 3305/4885NMT2 3870/4885SLC15A2 3106/4885
US-20050260275-A1 Encapsulated peptide copper complexes and compositions and methods related thereto NGLY1, CUTA, CTRC NMT1 1724/4885NMT2 2293/4885SLC15A2 981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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