SCHEMBL2241981

SCHEMBL2241981

C[C@H](N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)[O-].C[C@H](N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)[O-].[Cu+2]

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 3/20 0.44
GHSR Q92847 1/20 0.41
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
REN P00797 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4587279 0.98 CTRB1 (0.44) CTRB1GHSRHDAC3HDAC4HDAC1
SCHEMBL5598606 0.91 MME (0.46) CTRB1
SCHEMBL31184506 0.91 MME (0.46) CTRB1
SCHEMBL5598613 0.91 MME (0.46) CTRB1
SCHEMBL4587272 0.90 MME (0.46) CTRB1
SCHEMBL2241975 0.90 MME (0.46) CTRB1
SCHEMBL2813160 0.89 CTRB1 (0.33) CTRB1
SCHEMBL2244570 0.88 CTSC (0.40) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL4587808 0.87 CTRB1 (0.33) CTRB1
SCHEMBL4589444 0.86 CTSC (0.40) HDAC3HDAC4HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110206790-A1 Antimicrobial Foamable Soaps OHSO CLEAN, INC 2011-08-25 US disclosed
EP-2350252-A2 ANTIMICROBIAL FOAMABLE SOAPS Ohso Clean, Inc. (US) 2011-08-03 EP disclosed
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS PROCYTE CORPORATION (US) 2010-09-30 US disclosed
WO-2010059366-A2 ANTIMICROBIAL FOAMABLE SOAPS OHSO CLEAN, INC. (US) 2010-05-27 WO disclosed
EP-1613302-B1 PRESERVED AND STABLE COMPOSITIONS CONTAINING PEPTIDE COPPER COMPLEXES AND METHODS RELATED THERETO PROCYTE CORP (US) 2009-12-23 EP disclosed
US-7179789-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2007-02-20 US disclosed
US-7128923-B2 Preserved and stable compositions containing peptide copper complexes and method related thereto PROCYTE CORPORATION (US) 2006-10-31 US disclosed
US-20060052287-A1 Polyethylene glycol - peptide copper complexes and compositions and methods related thereto PROCYTE CORPORATION (US) 2006-03-09 US disclosed
US-20050209130-A1 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-09-22 US disclosed
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PROCYTE CORPORATION (US) 2005-09-08 US disclosed
US-6927205-B2 Compositions and methods for treatment of psoriasis PROCYTE CORPORATION (US) 2005-08-09 US disclosed
US-6927206-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-08-09 US disclosed
EP-0765152-B1 STIMULATION OF HAIR GROWTH BY PEPTIDE-COPPER COMPLEXES PROCYTE CORP (US) 2001-11-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050209130-A1 Compositions and methods for treatment of rosacea CUTA, AOC1, RCN1 CTRB1 6/4885GHSR 759/4885HDAC3 4165/4885
US-20060052287-A1 Polyethylene glycol - peptide copper complexes and compositions and methods related thereto NGLY1, CUTA, TFRC CTRB1 90/4885GHSR 854/4885HDAC3 4836/4885
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS CUTA, TYR, EYA3 CTRB1 43/4885GHSR 529/4885HDAC3 4296/4885
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PTH1R, TSLP, CYP27B1 CTRB1 104/4885GHSR 1509/4885HDAC3 4471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.