SCHEMBL2244570

SCHEMBL2244570

NCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)[O-].NCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)[O-].[Cu+2]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSC P53634 2/20 0.40
SLC15A2 Q16348 1/20 0.40
REN P00797 3/20 0.39
MMP1 P03956 2/20 0.38
FCER2 P06734 2/20 0.38
KLKB1 P03952 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
QRFPR Q96P65 1/20 0.38
KDM1A O60341 1/20 0.38
MAOA P21397 1/20 0.38
ITGB3 P05106 1/20 0.37
ITGA2B P08514 1/20 0.37
PTPN1 P18031 1/20 0.37
CTSL P07711 1/20 0.37
CTSB P07858 1/20 0.37
CTSS P25774 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4589444 0.98 CTSC (0.40) CTSCSLC15A2RENMMP1FCER2
SCHEMBL5598789 0.91 MME (0.46) SLC15A2ITGB3ITGA2B
SCHEMBL5598794 0.91 MME (0.46) SLC15A2ITGB3ITGA2B
SCHEMBL30692732 0.91 MME (0.46) SLC15A2ITGB3ITGA2B
SCHEMBL2244563 0.90 MME (0.45) SLC15A2ITGB3ITGA2B
SCHEMBL4589435 0.90 MME (0.45) SLC15A2ITGB3ITGA2B
SCHEMBL2241981 0.88 CTRB1 (0.44) RENHDAC3HDAC4HDAC1HDAC2
SCHEMBL2811070 0.87 SLC15A2 (0.36) CTSCSLC15A2
SCHEMBL4587279 0.86 CTRB1 (0.44) RENHDAC3HDAC4HDAC1HDAC2
SCHEMBL25626461 0.85 ACE (0.48) QRFPRPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110206790-A1 Antimicrobial Foamable Soaps OHSO CLEAN, INC 2011-08-25 US disclosed
EP-2350252-A2 ANTIMICROBIAL FOAMABLE SOAPS Ohso Clean, Inc. (US) 2011-08-03 EP disclosed
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS PROCYTE CORPORATION (US) 2010-09-30 US disclosed
WO-2010059366-A2 ANTIMICROBIAL FOAMABLE SOAPS OHSO CLEAN, INC. (US) 2010-05-27 WO disclosed
EP-1613302-B1 PRESERVED AND STABLE COMPOSITIONS CONTAINING PEPTIDE COPPER COMPLEXES AND METHODS RELATED THERETO PROCYTE CORP (US) 2009-12-23 EP disclosed
US-7179789-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2007-02-20 US disclosed
US-7128923-B2 Preserved and stable compositions containing peptide copper complexes and method related thereto PROCYTE CORPORATION (US) 2006-10-31 US disclosed
US-20060052287-A1 Polyethylene glycol - peptide copper complexes and compositions and methods related thereto PROCYTE CORPORATION (US) 2006-03-09 US disclosed
US-20050209130-A1 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-09-22 US disclosed
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PROCYTE CORPORATION (US) 2005-09-08 US disclosed
US-6927206-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-08-09 US disclosed
US-6927205-B2 Compositions and methods for treatment of psoriasis PROCYTE CORPORATION (US) 2005-08-09 US disclosed
EP-0765152-B1 STIMULATION OF HAIR GROWTH BY PEPTIDE-COPPER COMPLEXES PROCYTE CORP (US) 2001-11-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050209130-A1 Compositions and methods for treatment of rosacea CUTA, AOC1, RCN1 CTSC 424/4885SLC15A2 2091/4885REN 695/4885
US-20060052287-A1 Polyethylene glycol - peptide copper complexes and compositions and methods related thereto NGLY1, CUTA, TFRC CTSC 292/4885SLC15A2 1553/4885REN 3587/4885
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS CUTA, TYR, EYA3 CTSC 975/4885SLC15A2 2514/4885REN 3538/4885
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PTH1R, TSLP, CYP27B1 CTSC 1642/4885SLC15A2 3106/4885REN 947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.