Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 17/20 | 0.84 |
| ▸ | NPC1 | O15118 | 15/20 | 0.84 |
| ▸ | MAPT | P10636 | 12/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.84 |
| ▸ | MEN1 | O00255 | 9/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.84 |
| ▸ | TP53 | P04637 | 9/20 | 0.84 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.84 |
| ▸ | HPGD | P15428 | 5/20 | 0.84 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.84 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.84 |
| ▸ | RELA | Q04206 | 2/20 | 0.84 |
| ▸ | GFER | P55789 | 3/20 | 0.74 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.66 |
| ▸ | CASP3 | P42574 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2247122 | 0.91 | RAB9A (1.00) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL2488592 | 0.87 | RAB9A (0.96) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL30296348 | 0.87 | RAB9A (0.96) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL29404722 | 0.86 | RAB9A (1.00) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL31696797 | 0.86 | RAB9A (0.93) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL1852701 | 0.86 | RAB9A (1.00) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL25989646 | 0.85 | RAB9A (0.74) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL2245029 | 0.83 | RAB9A (1.00) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL27188297 | 0.82 | MAPT (0.66) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL19380022 | 0.82 | MAPT (0.79) | RAB9ANPC1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240109850-A1 | Covalent PPARG inverse-agonists | BAYER AKTIENGESELLSCHAFT (DE) | 2024-04-04 | — | — | US | disclosed |
| US-20230233531-A1 | USE OF NON-STEROIDAL ANTI-INFLAMMATORY COMPOUNDS FOR TREATMENT OF INFLAMMATION | UNIVERSITY OF HOUSTON SYSTEM | 2023-07-27 | — | — | US | disclosed |
| US-20230233531-A1 | USE OF NON-STEROIDAL ANTI-INFLAMMATORY COMPOUNDS FOR TREATMENT OF INFLAMMATION | UNIVERSITY OF HOUSTON SYSTEM | 2023-07-27 | — | — | US | disclosed |
| EP-3251694-A1 | DRUG COMBINATIONS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | Summit (Oxford) Limited (GB) | 2017-12-06 | — | — | EP | disclosed |
| US-20140018320-A1 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2014-01-16 | — | — | US | disclosed |
| US-20140011782-A1 | DRUG COMBINATIONS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2014-01-09 | — | — | US | disclosed |
| US-8518980-B2 | Treatment of Duchenne muscular dystrophy | SUMMIT CORPORATION PLC (GB) | 2013-08-27 | — | — | US | disclosed |
| US-8501713-B2 | Drug combinations for the treatment of duchenne muscular dystrophy | SUMMIT CORPORATION PLC (GB) | 2013-08-06 | — | — | US | disclosed |
| US-8330039-B2 | Solar cell modules with poly(vinyl butyral) encapsulant comprising unsaturated heterocyclic compound | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-11 | — | — | US | disclosed |
| US-8193372-B2 | Phosphothiophene and phosphothiazole HCV polymerase inhibitors | IDENIX PHARMACEUTICALS, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| EP-2380208-A1 | SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND | E. I. du Pont de Nemours and Company (US) | 2011-10-26 | — | — | EP | disclosed |
| US-20110195932-A1 | Drug Combinations for the Treatment of Duchenne Muscular Dystrophy | SUMMIT (OXFORD) LIMITED (GB) | 2011-08-11 | — | — | US | disclosed |
| US-20100233123-A1 | PHOSPHOTHIOPHENE AND PHOSPHOTHIAZOLE HCV POLYMERASE INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | US | disclosed |
| WO-2010085664-A1 | SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-29 | — | — | WO | disclosed |
| US-20100180947-A1 | SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-22 | — | — | US | disclosed |
| US-20090075938-A1 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT (OXFORD) LIMITED (GB) | 2009-03-19 | — | — | US | disclosed |
| EP-1986633-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | Summit Corporation Plc (GB) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007091106-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2007-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233531-A1 | USE OF NON-STEROIDAL ANTI-INFLAMMATORY COMPOUNDS FOR TREATMENT OF INFLAMMATION | PTGES, PTGES2, PTGES3 | RAB9A 4016/4885NPC1 1269/4885MAPT 810/4885 |
| US-20110195932-A1 | Drug Combinations for the Treatment of Duchenne Muscular Dystrophy | PYGM, CPT1B, GYS1 | RAB9A 3748/4885NPC1 2477/4885MAPT 3113/4885 |
| US-20140011782-A1 | DRUG COMBINATIONS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | PYGM, CPT1B, GYS1 | RAB9A 3748/4885NPC1 2477/4885MAPT 3113/4885 |
| US-20140018320-A1 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | NR0B1, NR0B2, NR3C1 | RAB9A 4325/4885NPC1 3637/4885MAPT 4858/4885 |
| US-20090075938-A1 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | NR0B1, NR0B2, NR3C1 | RAB9A 4325/4885NPC1 3637/4885MAPT 4858/4885 |
| US-20240109850-A1 | Covalent PPARG inverse-agonists | PPARG, PPARD, PPARA | RAB9A 1805/4885NPC1 1079/4885MAPT 4826/4885 |
| US-20100233123-A1 | PHOSPHOTHIOPHENE AND PHOSPHOTHIAZOLE HCV POLYMERASE INHIBITORS | PPP3CB, POLR2E, PSAT1 | RAB9A 3339/4885NPC1 3712/4885MAPT 1176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.