Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.30 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL22426275 | 0.93 | ANPEP (0.47) | ANPEPTSHRLMNATHRBPCSK9 | |
| SCHEMBL1237 | 0.93 | ANPEP (0.53) | ANPEPTSHRLMNATHRBPCSK9 | |
| SCHEMBL10899969 | 0.93 | ANPEP (0.53) | ANPEPTSHRLMNATHRBPCSK9 | |
| SCHEMBL3887127 | 0.89 | ANPEP (0.50) | ANPEPTSHRLMNATHRBPCSK9 | |
| SCHEMBL51210 | 0.89 | ANPEP (0.50) | ANPEPTSHRLMNATHRBPCSK9 | |
| SCHEMBL9814415 | 0.89 | ANPEP (0.50) | ANPEPTSHRLMNATHRBPCSK9 | |
| SCHEMBL952691 | 0.89 | ANPEP (0.50) | ANPEPTSHRLMNATHRBPCSK9 | |
| Ammonia Solution, Strong SCHEMBL28825800 | 0.89 | ANPEP (0.50) | ANPEPTSHRLMNATHRBPCSK9 | |
| SCHEMBL88650 | 0.81 | TSHR (0.50) | ANPEPTSHRLMNATHRBALDH1A1 | |
| SCHEMBL11524980 | 0.81 | TSHR (0.50) | ANPEPTSHRLMNATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3597630-B1 | DISSIMILAR-METAL SALT ASSEMBLY WHICH IS DENDRIMER HAVING FOUR OR MORE TYPES OF DISSIMILAR-METAL SALT COMPOUNDS PRECISELY INTEGRATED THEREIN, AND PRODUCTION METHOD FOR SUBNANO METAL PARTICLES | TOKYO INST TECH (JP) | 2021-09-15 | — | — | EP | disclosed |
| US-10781290-B2 | Multiple metal salt assembly of dendrimer having four or more types of multiple-metal salt compound precisely assembled, and method for producing subnano metal particles | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2020-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10781290-B2 | Multiple metal salt assembly of dendrimer having four or more types of multiple-metal salt compound precisely assembled, and method for producing subnano metal particles | PICALM, SIN3A, KCNN3 | ANPEP 1517/4885TSHR 2778/4885LMNA 3135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.