Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | NPC1 | O15118 | 6/20 | 1.00 |
| ▸ | RAB9A | P51151 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.79 |
| ▸ | HPGD | P15428 | 4/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.76 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.62 |
| ▸ | MMP2 | P08253 | 3/20 | 0.61 |
| ▸ | MMP13 | P45452 | 3/20 | 0.61 |
| ▸ | MMP9 | P14780 | 2/20 | 0.61 |
| ▸ | MMP8 | P22894 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27202469 | 0.86 | SMN1; SMN2 (0.85) | SMN1; SMN2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL13679621 | 0.83 | MAPT (0.71) | SMN1; SMN2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL2244921 | 0.82 | MMP2 (0.78) | SMN1; SMN2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL2249504 | 0.81 | MAPT (0.81) | SMN1; SMN2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL29675227 | 0.80 | MMP2 (0.78) | SMN1; SMN2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL15702637 | 0.80 | MMP2 (0.78) | SMN1; SMN2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL8820296 | 0.80 | MMP2 (0.82) | SMN1; SMN2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL8870051 | 0.79 | MMP2 (0.80) | SMN1; SMN2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL8820325 | 0.79 | MMP2 (0.80) | SMN1; SMN2MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL8820321 | 0.79 | MMP2 (0.80) | SMN1; SMN2MAPTNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240131007-A1 | METHODS AND COMPOSITIONS FOR PICORNAVIRUS ANTI-VIRAL AGENTS | UNIVERSITY OF CONNECTICUT | 2024-04-25 | — | — | US | disclosed |
| EP-3251694-A1 | DRUG COMBINATIONS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | Summit (Oxford) Limited (GB) | 2017-12-06 | — | — | EP | disclosed |
| US-20140018320-A1 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2014-01-16 | — | — | US | disclosed |
| US-20140011782-A1 | DRUG COMBINATIONS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2014-01-09 | — | — | US | disclosed |
| US-8518980-B2 | Treatment of Duchenne muscular dystrophy | SUMMIT CORPORATION PLC (GB) | 2013-08-27 | — | — | US | disclosed |
| CN-101420950-B | Treatment of duchenne muscular dystrophy | SUMMIT CORP PLC | 2012-04-18 | — | — | CN | disclosed |
| US-20110195932-A1 | Drug Combinations for the Treatment of Duchenne Muscular Dystrophy | SUMMIT (OXFORD) LIMITED (GB) | 2011-08-11 | — | — | US | disclosed |
| CN-101678107-A | Pharmaceutical composition for treating Duchenne muscular dystrophy | SUMMIT CORP PLC | 2010-03-24 | — | — | CN | disclosed |
| CN-101420950-A | Treatment of Duchenne muscular dystrophy | SUMMIT CORP PLC (GB) | 2009-04-29 | — | — | CN | disclosed |
| US-20090075938-A1 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT (OXFORD) LIMITED (GB) | 2009-03-19 | — | — | US | disclosed |
| EP-1986633-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | Summit Corporation Plc (GB) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007091106-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2007-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240131007-A1 | METHODS AND COMPOSITIONS FOR PICORNAVIRUS ANTI-VIRAL AGENTS | RNASEH1, HNRNPA2B1, HNRNPA1 | SMN1; SMN2 847/4885MAPT 3821/4885NPC1 824/4885 |
| US-20110195932-A1 | Drug Combinations for the Treatment of Duchenne Muscular Dystrophy | PYGM, CPT1B, GYS1 | SMN1; SMN2 4/4885MAPT 3113/4885NPC1 2477/4885 |
| US-20140011782-A1 | DRUG COMBINATIONS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | PYGM, CPT1B, GYS1 | SMN1; SMN2 4/4885MAPT 3113/4885NPC1 2477/4885 |
| US-20140018320-A1 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | NR0B1, NR0B2, NR3C1 | SMN1; SMN2 9/4885MAPT 4858/4885NPC1 3637/4885 |
| US-20090075938-A1 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | NR0B1, NR0B2, NR3C1 | SMN1; SMN2 9/4885MAPT 4858/4885NPC1 3637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.