SCHEMBL22431371

SCHEMBL22431371

Cc1ccccc1N1c2ncccc2N(N)[C@@H]1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.37
▸ ALDH1A1 P00352 3/20 0.37
▸ HPGD P15428 2/20 0.37
▸ TSHR P16473 2/20 0.37
▸ TDP1 Q9NUW8 2/20 0.37
▸ NOS3 P29474 1/20 0.37
▸ NOS1 P29475 1/20 0.37
▸ NOS2 P35228 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ ALOX15 P16050 1/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ HKDC1 Q2TB90 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ FLT3 P36888 1/20 0.36
▸ GSK3B P49841 1/20 0.36
▸ KMT2A Q03164 3/20 0.33
▸ NPSR1 Q6W5P4 2/20 0.33
▸ LMNA P02545 2/20 0.33
▸ MEN1 O00255 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22781118 1.00 KDM4E (0.37) KDM4EALDH1A1HPGDTSHRTDP1
SCHEMBL22627514 0.88 KDM4E (0.37) KDM4EALDH1A1HPGDTSHRTDP1
SCHEMBL22781161 0.88 KDM4E (0.37) KDM4EALDH1A1HPGDTSHRTDP1
SCHEMBL22781162 0.86 ALDH1A1 (0.34) KDM4EALDH1A1HPGDTSHRTDP1
SCHEMBL22431370 0.86 ALDH1A1 (0.34) KDM4EALDH1A1HPGDTSHRTDP1
SCHEMBL23998675 0.86 ALDH1A1 (0.41) KDM4EALDH1A1HPGDTSHRTDP1
SCHEMBL11995100 0.83 KDM4E (0.38) KDM4EALDH1A1HPGDTSHRTDP1
SCHEMBL16726495 0.83 KDM4E (0.38) KDM4EALDH1A1HPGDTSHRTDP1
SCHEMBL24444108 0.83 KDM4E (0.38) KDM4EALDH1A1HPGDTSHRTDP1
SCHEMBL20732583 0.82 ALDH1A1 (0.37) KDM4EALDH1A1HPGDTSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357296-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 — — US disclosed
US-20230337521-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 — — US disclosed
US-11737349-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-22 — — US disclosed
US-20230157154-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-18 — — US disclosed
US-20230118611-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-20 — — US disclosed
US-20230071261-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-03-09 — — US disclosed
US-20220399510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-12-15 — — US disclosed
US-20220324892-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-10-13 — — US disclosed
US-20220298190-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-09-22 — — US disclosed
US-20220302395-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-09-22 — — US disclosed
US-11374181-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-06-28 — — US disclosed
US-20220173337-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-06-02 — — US disclosed
US-20220052275-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-02-17 — — US disclosed
US-20210399237-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-12-23 — — US disclosed
US-20210380617-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-12-09 — — US disclosed
US-20210167302-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-06-03 — — US disclosed
US-20210094978-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-04-01 — — US disclosed
US-20210050529-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-02-18 — — US disclosed
US-20200350502-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-05 — — US disclosed
US-20200295277-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-09-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (17 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200350502-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBP, OSBPL3, OSBP2 KDM4E 4178/4885ALDH1A1 227/4885HPGD 2086/4885
US-20230157154-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, GLRA3 KDM4E 3127/4885ALDH1A1 680/4885HPGD 3380/4885
US-20220298190-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, LARP1 KDM4E 3331/4885ALDH1A1 690/4885HPGD 1306/4885
US-20210399237-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 KDM4E 3120/4885ALDH1A1 139/4885HPGD 854/4885
US-20230357296-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, OXER1, LBR KDM4E 4190/4885ALDH1A1 1046/4885HPGD 2099/4885
US-20230118611-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, NR4A1 KDM4E 2433/4885ALDH1A1 1121/4885HPGD 1501/4885
US-11737349-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OTC KDM4E 1544/4885ALDH1A1 402/4885HPGD 855/4885
US-20220173337-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OTC KDM4E 1544/4885ALDH1A1 402/4885HPGD 855/4885
US-20230337521-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, NR1H2 KDM4E 1372/4885ALDH1A1 600/4885HPGD 3721/4885
US-20220324892-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, ICOSLG, OCIAD1 KDM4E 3756/4885ALDH1A1 587/4885HPGD 1557/4885
US-20220399510-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, KCNH3, KCNH2 KDM4E 1186/4885ALDH1A1 1237/4885HPGD 4040/4885
US-20220052275-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OTC KDM4E 1544/4885ALDH1A1 402/4885HPGD 855/4885
US-20210380617-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, CRKL, ROS1 KDM4E 1478/4885ALDH1A1 1778/4885HPGD 4773/4885
US-20220302395-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, LEF1 KDM4E 3601/4885ALDH1A1 460/4885HPGD 1833/4885
US-20230071261-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, LOXL1, OCIAD2 KDM4E 3634/4885ALDH1A1 43/4885HPGD 426/4885
US-20210094978-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EPCAM, LEF1 KDM4E 3978/4885ALDH1A1 187/4885HPGD 2965/4885
US-20200295277-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OTC KDM4E 1544/4885ALDH1A1 402/4885HPGD 855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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