Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.46 |
| ▸ | PGR | P06401 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22453128 | 0.91 | LMNA (0.56) | LMNAALDH1A1EPHX2PGRCYP1A2 | |
| SCHEMBL22453610 | 0.81 | EPHX2 (0.50) | LMNAEPHX2PGRMAPTCYP1A2 | |
| SCHEMBL22453165 | 0.78 | ALDH1A1 (0.79) | LMNAALDH1A1EPHX2PGRMAPT | |
| SCHEMBL22453686 | 0.75 | NPC1 (0.67) | LMNAALDH1A1EPHX2PGRMAPT | |
| SCHEMBL22452805 | 0.75 | FABP4 (0.47) | LMNAALDH1A1EPHX2PGRMAPT | |
| SCHEMBL3179232 | 0.74 | MEN1 (0.45) | LMNAALDH1A1EPHX2PGRCYP1A2 | |
| SCHEMBL5006770 | 0.74 | EPHX2 (0.46) | LMNAALDH1A1EPHX2CYP1A2CYP2C9 | |
| SCHEMBL28090104 | 0.74 | GRIN1 (0.49) | LMNAALDH1A1EPHX2CYP1A2CYP2C9 | |
| SCHEMBL22453480 | 0.73 | MAPT (0.52) | ALDH1A1EPHX2PGRMAPTCYP1A2 | |
| SCHEMBL22452496 | 0.72 | EPHX2 (0.41) | LMNAEPHX2PGRMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |