Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.35 |
| ▸ | DHFR | P00374 | 4/20 | 0.34 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PDE8A | O60658 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4700034 | 0.93 | NPC1 (0.36) | TLR7DHFRDCPSNPC1USP2 | |
| SCHEMBL4702114 | 0.81 | ACHE (0.38) | TLR7DHFRTP53ALDH1A1 | |
| SCHEMBL2513546 | 0.79 | LMNA (0.33) | TLR7DHFRDCPSNPC1TP53 | |
| SCHEMBL2241078 | 0.78 | ALDH1A1 (0.35) | TLR7DHFRNPC1TP53RAB9A | |
| SCHEMBL4792173 | 0.78 | TP53 (0.34) | TLR7DHFRDCPSNPC1TP53 | |
| SCHEMBL4704199 | 0.78 | KCNA5 (0.36) | TLR7DHFRNPC1TP53RAB9A | |
| SCHEMBL2243546 | 0.77 | DHFR (0.33) | TLR7DHFRALDH1A1 | |
| SCHEMBL4792910 | 0.76 | TLR8 (0.37) | TLR7DHFRDCPSTP53TLR8 | |
| SCHEMBL1775006 | 0.76 | MAPT (0.36) | TLR7DHFRNPC1TP53RAB9A | |
| SCHEMBL4794357 | 0.76 | PIK3CB (0.33) | TLR7DHFRDCPSNPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207725-A1 | CHIRAL FUSED [1,2]IMIDAZO[4,5-c] RING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY | 2011-08-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207725-A1 | CHIRAL FUSED [1,2]IMIDAZO[4,5-c] RING COMPOUNDS | IFNAR1, IFNG, IL4 | TLR7 124/4885DHFR 160/4885DCPS 3088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.