Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MITF | O75030 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23507237 | 0.93 | SMN1; SMN2 (0.58) | SMN1; SMN2RAB9AKMT2ALMNAHTT | |
| SCHEMBL2118284 | 0.78 | ATM (0.55) | SMN1; SMN2RAB9AKMT2ALMNAHTT | |
| SCHEMBL218867 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9AKMT2ALMNAHTT | |
| SCHEMBL20360513 | 0.76 | SMN1; SMN2 (0.89) | SMN1; SMN2RAB9AKMT2ALMNAHTT | |
| SCHEMBL6736049 | 0.74 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9AKMT2ALMNAHTT | |
| Hydrochloric Acid SCHEMBL7036575 | 0.74 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9AKMT2ALMNAHTT | |
| SCHEMBL23529356 | 0.74 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9AKMT2ALMNAHTT | |
| SCHEMBL1937600 | 0.74 | LMNA (0.54) | SMN1; SMN2RAB9AKMT2ALMNAHTT | |
| SCHEMBL27938343 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2RAB9AKMT2ALMNAHTT | |
| Cyclooctanol SCHEMBL5303490 | 0.73 | RAB9A (0.60) | SMN1; SMN2RAB9AKMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11655203-B2 | Nitration | ETH ZURICH (CH) | 2023-05-23 | — | — | US | disclosed |
| US-11655203-B2 | Nitration | ETH ZURICH (CH) | 2023-05-23 | — | — | US | disclosed |
| US-11655203-B2 | Nitration | ETH ZURICH (CH) | 2023-05-23 | — | — | US | disclosed |
| US-20220009875-A1 | NITRATION | ETH ZURICH (CH) | 2022-01-13 | — | — | US | disclosed |
| US-20220009875-A1 | NITRATION | ETH ZURICH (CH) | 2022-01-13 | — | — | US | disclosed |
| EP-3717464-B1 | NITRATION | ETH ZUERICH (CH) | 2021-06-16 | — | — | EP | disclosed |
| EP-3717464-B1 | NITRATION | ETH ZUERICH (CH) | 2021-06-16 | — | — | EP | disclosed |
| EP-3717464-A1 | NITRATION | ETH Zurich (CH) | 2020-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220009875-A1 | NITRATION | NOS1, NOS2, NOS3 | SMN1; SMN2 1222/4885RAB9A 3353/4885KMT2A 2374/4885 |
| US-11655203-B2 | Nitration | NOS1, NOS2, NOS3 | SMN1; SMN2 1222/4885RAB9A 3353/4885KMT2A 2374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.