Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL29727670 | 1.00 | LMNA (0.41) | LMNATDP1MEN1KMT2A | |
| SCHEMBL2721232 | 0.97 | LMNA (0.44) | LMNATDP1MEN1KMT2A | |
| SCHEMBL47326 | 0.85 | RXRA (0.37) | LMNATDP1MEN1KMT2A | |
| SCHEMBL29869219 | 0.85 | RXRA (0.37) | LMNATDP1MEN1KMT2A | |
| SCHEMBL11852597 | 0.85 | G6PD (0.38) | LMNAMEN1KMT2A | |
| SCHEMBL13962645 | 0.84 | ALDH1A1 (0.34) | TDP1MEN1KMT2A | |
| SCHEMBL224968 | 0.84 | RXRA (0.36) | LMNATDP1MEN1KMT2A | |
| SCHEMBL6027095 | 0.84 | MAPT (0.42) | LMNAMEN1KMT2A | |
| Potassium SCHEMBL559580 | 0.84 | RXRA (0.36) | LMNATDP1MEN1KMT2A | |
| SCHEMBL2721236 | 0.84 | RXRA (0.36) | LMNATDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113337138-B | Indole cyanine dye | 天津全和诚科技有限责任公司 | 2022-08-09 | — | — | CN | claimed |
| CN-113462186-A | sulfo-Cy 3 carboxylic acid fluorescent dye and preparation process thereof | 江西高信前沿科技有限公司 | 2021-10-01 | — | — | CN | claimed |
| CN-113337138-A | Novel indole cyanine dye | 天津全和诚科技有限责任公司 | 2021-09-03 | — | — | CN | claimed |
| US-20260117070-A1 | NEAR-INFRARED FLUORESCENT HEPTAMETHINE DYE CONJUGATES WITH FAVORABLE BLEACHING PROPERTIES | HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM GESUNDHEIT & UMWELT GMBH (DE) | 2026-04-30 | — | — | US | disclosed |
| US-20250275943-A1 | COMPOSITION FOR CANCER DIAGNOSIS TARGETING TUMOR AND/OR TUMOR MICROENVIRONMENT AND USE THEREOF | The General Hospital Cooperation d/b/a Massachusetts General Hospital (MGH) | 2025-09-04 | — | — | US | disclosed |
| WO-2025095666-A1 | NOVEL OXOCYANINE-BASED COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 포항공과대학교 산학협력단 | 2025-05-08 | — | — | WO | disclosed |
| EP-4529551-A1 | NEAR-INFRARED FLUORESCENT HEPTAMETHINE DYE CONJUGATES WITH FAVORABLE BLEACHING PROPERTIES | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2025-04-02 | — | — | EP | disclosed |
| WO-2023227601-A1 | NEAR-INFRARED FLUORESCENT HEPTAMETHINE DYE CONJUGATES WITH FAVORABLE BLEACHING PROPERTIES | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2023-11-30 | — | — | WO | disclosed |
| US-20220387632-A1 | RENAL CLEARABLE FLUORESCENT CONTRAST AGENT WITH INCREASED TUMOR SPECIFICITY, AND IMAGING METHOD USING SAME | NAWOOVISION CO., LTD. (KP) | 2022-12-08 | — | — | US | disclosed |
| CN-113337138-B | Indole cyanine dye | 天津全和诚科技有限责任公司 | 2022-08-09 | — | — | CN | disclosed |
| US-20210338841-A1 | Imaging Agents | SCINTOMICS GMBH (DE) | 2021-11-04 | — | — | US | disclosed |
| US-6538129-B1 | Luminescent compounds | Terpetschnig, Ewald A. | 2003-03-25 | — | — | US | disclosed |
| US-6448008-B1 | IMMUNOLOGICAL BINDING REAGENT LABELLED WITH A FLUORESCENT COMPOUND AND METHOD OF ASSAYING AN ANALYTE IN A SAMPLE COMPRISING CONTACTING A NUCLEIC ACID PROBE OR AN IMMUNOLOGICALLY BINDING REAGENT LABELLED WITH A FLUORESCENT | INNOSENSE, S.R.L. (IT) | 2002-09-10 | — | — | US | disclosed |
| EP-0898596-B1 | SQUARATE DYES AND THEIR USE IN FLUORESCENT SEQUENCING METHOD | AMERSHAM PHARM BIOTECH UK LTD (GB) | 2001-08-29 | — | — | EP | disclosed |
| EP-1078023-A1 | LUMINESCENT COMPOUNDS | Terpetschnig, Ewald A. (US) | 2001-02-28 | — | — | EP | disclosed |
| EP-1065250-A1 | New fluorescent cyanine labels containing a sulfamido linker arm | Innosense S.r.l. (IT) | 2001-01-03 | — | — | EP | disclosed |
| US-6140494-A | INCREASED WATER SOLUBILITY, INCREASED PHOTOSTABILITY, BRIGHTNESS AND THE POTENTIAL REDUCTION OF INTERACTIONS WITH SURROUNDINGS | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 2000-10-31 | — | — | US | disclosed |
| WO-1999051702-A1 | LUMINESCENT COMPOUNDS | TERPETSCHNIG EWALD A (US) | 1999-10-14 | — | — | WO | disclosed |
| EP-0898596-A1 | SQUARATE DYES AND THEIR USE IN FLUORESCENT SEQUENCING METHOD | Amersham Pharmacia Biotech UK Limited (GB) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040104-A1 | SQUARATE DYES AND THEIR USE IN FLUORESCENT SEQUENCING METHOD | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 1997-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260117070-A1 | NEAR-INFRARED FLUORESCENT HEPTAMETHINE DYE CONJUGATES WITH FAVORABLE BLEACHING PROPERTIES | CBR1, CBR3, NR2E3 | LMNA 1557/4885TDP1 3164/4885MEN1 2322/4885 |
| US-20210338841-A1 | Imaging Agents | HNRNPF, ANXA5, TFEB | LMNA 1392/4885TDP1 1059/4885MEN1 775/4885 |
| US-20220387632-A1 | RENAL CLEARABLE FLUORESCENT CONTRAST AGENT WITH INCREASED TUMOR SPECIFICITY, AND IMAGING METHOD USING SAME | RCC2, REN, VHL | LMNA 3256/4885TDP1 4513/4885MEN1 129/4885 |
| US-20250275943-A1 | COMPOSITION FOR CANCER DIAGNOSIS TARGETING TUMOR AND/OR TUMOR MICROENVIRONMENT AND USE THEREOF | FOLR1, FOLR2, MSR1 | LMNA 3002/4885TDP1 4237/4885MEN1 996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.