SCHEMBL226109

SCHEMBL226109

Clc1cccc(Cl)c1SSc1c(Cl)cccc1Cl

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.47
CYP1A2 P05177 3/20 0.47
TSHR P16473 4/20 0.47
LMNA P02545 1/20 0.47
ALDH1A1 P00352 4/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
SOD1 P00441 1/20 0.38
TAAR1 Q96RJ0 1/20 0.36
PNMT P11086 1/20 0.36
NR4A2 P43354 1/20 0.36
TERT O14746 1/20 0.33
AKR1B1 P15121 1/20 0.33
RHEB Q15382 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9805923 0.81 TAAR1 (0.43) CYP2A6CYP1A2TSHRLMNAMEN1
SCHEMBL9264116 0.81 ALDH1A1 (0.39) CYP2A6CYP1A2TSHRLMNAALDH1A1
SCHEMBL28715207 0.80 CYP1A2 (0.47) CYP2A6CYP1A2TSHRLMNAALDH1A1
SCHEMBL4128904 0.78 CYP1A2 (0.45) CYP2A6CYP1A2TSHRLMNAALDH1A1
SCHEMBL16703511 0.77 PNMT (0.41) CYP2A6CYP1A2TSHRLMNAKMT2A
SCHEMBL24211432 0.75 CYP1A2 (0.43) CYP2A6CYP1A2TSHRLMNAALDH1A1
SCHEMBL5594801 0.75 CYP1A2 (0.43) CYP2A6CYP1A2TSHRLMNAALDH1A1
SCHEMBL10378510 0.75 CYP1A2 (0.43) CYP2A6CYP1A2TSHRLMNAALDH1A1
SCHEMBL5594805 0.75 CYP1A2 (0.43) CYP2A6CYP1A2TSHRLMNAALDH1A1
SCHEMBL7278243 0.74 TSHR (0.61) CYP1A2TSHRLMNAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1073 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140295994-A1 GOLF BALL DUNLOP SPORTS CO., LTD. (JP) 2014-10-02 US claimed
US-6998444-B2 Vulcanization accelerator in crosslinked cis-polybutadiene core for increase compression and low coefficient of restitution, without causing any isomerism; use small amounts of crosslinker zinc diacrylate ACUSHNET COMPANY (US) 2006-02-14 US claimed
US-20050256274-A1 Golf ball core compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-17 US claimed
US-6960629-B2 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY (US) 2005-11-01 US claimed
US-20040230006-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-18 US claimed
US-20040230005-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY 2004-11-18 US claimed
US-5861465-A VULCANIZED RUBBER CONTAINING A DIPHENYL AND DINAPHTHYL DISULFIDE; IMPACT STRENGTH, RESILIENCE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 1999-01-19 US claimed
US-5153305-A From diaryl disulfide; mild conditions using organometallic catalyst RESEARCH INSTITUTE FOR PRODUCTION DEVELOPMENT (JP) 1992-10-06 US claimed
US-12623120-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-05-12 US disclosed
US-12600837-B2 Rubber composition and crosslinked rubber molded product SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-04-14 US disclosed
US-20260097269-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-04-09 US disclosed
US-20260097267-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-04-09 US disclosed
EP-4527473-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2026-03-25 EP disclosed
US-12544628-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-02-10 US disclosed
EP-0150255-B1 Pyrrolo[1,2-a]imidazole and imidazo[1,2-a]pyridine immunomodulators FISONS CORPORATION (US) 1990-12-12 EP disclosed
US-4603206-A ALCOHOLS, ETHERS FROM MERCAPTANS, SULFIDES;POSITIVE HALOGENATING AGENT; ALCOHOL; IMMUNOMODULATORS PENNWALT CORPORATION (US) 1986-07-29 US disclosed
US-4560758-A IMMUNOMODULATORS PENNWALT CORPORATION (US) 1985-12-24 US disclosed
US-4551535-A SULFIDING IN THE PRESENCE OF A BASE PENNWALT CORPORATION (US) 1985-11-05 US disclosed
EP-0150255-A2 Pyrrolo[1,2-a]imidazole and imidazo[1,2-a]pyridine immunomodulators FISONS CORPORATION (US) 1985-08-07 EP disclosed
US-4507481-A IMMUNOMODULATORS PENNWALT CORPORATION (US) 1985-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12544628-B2 Golf ball KIF5A, KIF5C, SURF4 CYP2A6 3227/4885CYP1A2 3050/4885TSHR 1538/4885
US-12623120-B2 Golf ball HSPH1, HSP90AB1, DYNC1H1 CYP2A6 4080/4885CYP1A2 3527/4885TSHR 3570/4885
US-20260097267-A1 GOLF BALL MYO1F, MYOF, MYOC CYP2A6 3393/4885CYP1A2 3677/4885TSHR 3270/4885
US-20260097269-A1 GOLF BALL HSP90AB1, HSP90AA1, HSP90AB2P CYP2A6 2645/4885CYP1A2 3743/4885TSHR 4512/4885
US-12600837-B2 Rubber composition and crosslinked rubber molded product RER1, RIF1, SHC1 CYP2A6 4552/4885CYP1A2 3315/4885TSHR 2922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.